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Daily Application of a Toothpaste with Biomimetic Hydroxyapatite and Its Subjective Impact on Dentin Hypersensitivity, Tooth Smoothness, Tooth Whitening, Gum Bleeding, and Feeling of Freshness

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Dental practice, Bielefeld 33602, Germany
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Dental practice, Frankfurt am Main 60594, Germany
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Dental practice, Bad Harzburg 38667, Germany
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Dr. Kurt Wolff GmbH & Co. KG, Research Department, Bielefeld 33611, Germany
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Author to whom correspondence should be addressed.
Biomimetics 2020, 5(2), 17; https://doi.org/10.3390/biomimetics5020017
Received: 6 April 2020 / Revised: 16 April 2020 / Accepted: 24 April 2020 / Published: 28 April 2020
The aim of this observational study was to analyze the effect of a toothpaste with biomimetic zinc hydroxyapatite (HAP) on subjective parameters after a four-week home use. Patients with subjective dentin hypersensitivity were recruited at three dental practices in Germany and received a questionnaire with visual analogue scales and Likert scales both at baseline and follow-up. The questionnaire was specifically developed for this study and focused on questions about subjective parameters like dentin hypersensitivity, tooth surface texture, tooth color, and freshness after toothbrushing. Patients answered the questionnaire both at baseline and after a four-week home use (follow-up) of the HAP toothpaste. Data of 46 patients were analyzed by paired t-test and non-parametric Wilcoxon signed-rank test, respectively. Subjective parameters on dentin hypersensitivity were reduced after the four-week use of the HAP toothpaste (p < 0.001). Additionally, patients assessed their tooth surface as smoother (p < 0.001), tooth color as whiter (p = 0.003), and reported a stronger feeling of freshness after toothbrushing (p = 0.014) after four-week use of the HAP toothpaste compared to the previously used toothpaste. In conclusion, the tested toothpaste with biomimetic HAP is well-suited for individuals suffering from dentin hypersensitivity, because subjective symptoms on dentin hypersensitivity were reduced. Additionally, patients reported smoother and whiter teeth after using the HAP toothpaste. View Full-Text
Keywords: teeth; biomimetic hydroxyapatite; oral care; toothpaste; dentin hypersensitivity; observational study teeth; biomimetic hydroxyapatite; oral care; toothpaste; dentin hypersensitivity; observational study
MDPI and ACS Style

Steinert, S.; Zwanzig, K.; Doenges, H.; Kuchenbecker, J.; Meyer, F.; Enax, J. Daily Application of a Toothpaste with Biomimetic Hydroxyapatite and Its Subjective Impact on Dentin Hypersensitivity, Tooth Smoothness, Tooth Whitening, Gum Bleeding, and Feeling of Freshness. Biomimetics 2020, 5, 17.

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