# Enhanced Contactless Vital Sign Estimation from Real-Time Multimodal 3D Image Data

^{1}

^{2}

^{*}

## Abstract

**:**

## 1. Introduction

_{2}), respiration rate, body temperature, etc. is an important basic task in biomedical metrology. Conventional devices for such tasks mostly take contact-based measurement approaches. However, contact measurement has several disadvantages. Above all, contact with the body and skin raises the risk of skin irritation and germ contamination. Moreover, contact-based devices significantly limit the freedom of body movement of the patients, and hence, it could lead to severe discomforts. Therefore, the contactless estimation of vital signs using image sensors has continuously gained importance because of its advantages regarding hygiene and patient-friendliness.

_{2}conversion are to be empirically determined.

## 2. Multimodal 3D Imaging System

^{2}and, thus, within the eye safety limits [25]. The high-speed cameras of the stereo-vision setup and both the NIR cameras are equipped with band-pass optical filters with respective central wavelengths and a full-width at half-maximum (FWHM) of 50 nm. The GOBO projector contains a band-pass filter at 850 nm with a 50 nm FWHM in order to avoid possible spectral crosstalk between pattern projection and NIR cameras.

## 3. Algorithms

#### 3.1. Face Analysis

#### 3.2. 3D Face Tracking

#### 3.3. Vital Sign Estimation

_{2}value, can be calculated by calculating the AC and DC components at both 780 and 940 nm. In order to improve the stability of oxygen saturation estimation, the RR values should be averaged over a certain time window.

## 4. Results

#### 4.1. Body Temperature and Respiration Rate

#### 4.2. Heart Rate

#### 4.3. Oxygen Saturation

_{2}values and calculated RR values within 65 s. Both these variations are qualitatively consistent with each other in the course of time, and the Pearson moment correlation coefficient between them is 0.867. In Figure 12b, the result of the linear regression between RR and SpO

_{2}values is shown. In general, a linear relation can be found and the prediction of SpO

_{2}values based on RR is possible, though the data appear to be somewhat noisy and the coefficient of determination R

^{2}of the linear statistical model is 0.7521. Based on SpO

_{2}values estimated from the RR values using this linear model, the limits of agreement were determined according to the Bland–Altman method and are shown in Figure 12c. Here, the mean difference was zero, because the same ground truth values used for the fitting of the linear RR-to-SpO

_{2}conversion model were also used for the determination of LoAs, and the 95% confidence LoAs were −4.26% and 4.26%. Based on Figure 12a and the LoAs, it can be claimed that changes in the SpO

_{2}values by more than 5% could be detected with high reliability.

## 5. Summary and Discussion

## Author Contributions

## Funding

## Acknowledgments

## Conflicts of Interest

## References

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**Figure 1.**Multimodal 3D imaging system. 1/2: High-speed cameras at 850 nm, 3: High-speed GOes Before Optics (GOBO) projector at 850 nm, 4: Color camera, 5: NIR camera at 780 nm, 6: NIR camera at 940 nm, 7: Thermal camera, 8: Light emitting diode (LED) array at 780 and 940 nm.

**Figure 4.**(

**a**) Selection of region of interest (ROI) and feature points on the basis of face analysis in 2D color image, (

**b**) transformation of ROI and feature points into 3D space.

**Figure 7.**Extraction of primary photoplethysmographic (PPG) signal for heart rate estimation and enhanced NIR grey value signals for oxygen saturation estimation from 3D and NIR image data.

**Figure 9.**Estimation of respiration rate from the nostrils’ ROI: (

**a**) Temporal temperature signal, (

**b**) power density spectrum calculated from the respiration signal.

**Figure 10.**Estimation of one heart rate: (

**a**) Final PPG signal, (

**b**) power density spectrum calculated from the final PPG signal.

**Figure 11.**Continuous estimation of heart rate: (

**a**) Ground truth values and estimated values of heart rate within 80 s, (

**b**) difference between estimated heart rate and ground truth.

**Figure 12.**Continuous estimation of oxygen saturation: (

**a**) Ground truth SpO

_{2}values and ratio of ratios (RR) values within 65 s, (

**b**) linear regression between RR and SpO

_{2}values, (

**c**) difference between estimated SpO

_{2}and ground truth.

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**MDPI and ACS Style**

Zhang, C.; Gebhart, I.; Kühmstedt, P.; Rosenberger, M.; Notni, G.
Enhanced Contactless Vital Sign Estimation from Real-Time Multimodal 3D Image Data. *J. Imaging* **2020**, *6*, 123.
https://doi.org/10.3390/jimaging6110123

**AMA Style**

Zhang C, Gebhart I, Kühmstedt P, Rosenberger M, Notni G.
Enhanced Contactless Vital Sign Estimation from Real-Time Multimodal 3D Image Data. *Journal of Imaging*. 2020; 6(11):123.
https://doi.org/10.3390/jimaging6110123

**Chicago/Turabian Style**

Zhang, Chen, Ingo Gebhart, Peter Kühmstedt, Maik Rosenberger, and Gunther Notni.
2020. "Enhanced Contactless Vital Sign Estimation from Real-Time Multimodal 3D Image Data" *Journal of Imaging* 6, no. 11: 123.
https://doi.org/10.3390/jimaging6110123