Next Article in Journal
Hydrogels as Porogens for Nanoporous Inorganic Materials
Next Article in Special Issue
New Insights on the Role of Urea on the Dissolution and Thermally-Induced Gelation of Cellulose in Aqueous Alkali
Previous Article in Journal
Cryostructuring of Polymeric Systems. 49. Unexpected “Kosmotropic-Like” Impact of Organic Chaotropes on Freeze–Thaw-Induced Gelation of PVA in DMSO
Previous Article in Special Issue
Concepts for Developing Physical Gels of Chitosan and of Chitosan Derivatives
Article Menu
Issue 4 (December) cover image

Export Article

Open AccessCommunication

Evaluation of Hydrogels Based on Oxidized Hyaluronic Acid for Bioprinting

Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, 97070 Würzburg, Germany
Author to whom correspondence should be addressed.
Received: 15 August 2018 / Revised: 9 September 2018 / Accepted: 27 September 2018 / Published: 9 October 2018
(This article belongs to the Special Issue Polysaccharide Hydrogels)
Full-Text   |   PDF [1827 KB, uploaded 9 October 2018]   |  


In this study, we evaluate hydrogels based on oxidized hyaluronic acid, cross-linked with adipic acid dihydrazide, for their suitability as bioinks for 3D bioprinting. Aldehyde containing hyaluronic acid (AHA) is synthesized and cross-linked via Schiff Base chemistry with bifunctional adipic acid dihydrazide (ADH) to form a mechanically stable hydrogel with good printability. Mechanical and rheological properties of the printed and casted hydrogels are tunable depending on the concentrations of AHA and ADH cross-linkers. View Full-Text
Keywords: biofabrication; bioprinting; hyaluronic acid biofabrication; bioprinting; hyaluronic acid

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Weis, M.; Shan, J.; Kuhlmann, M.; Jungst, T.; Tessmar, J.; Groll, J. Evaluation of Hydrogels Based on Oxidized Hyaluronic Acid for Bioprinting. Gels 2018, 4, 82.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Gels EISSN 2310-2861 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top