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Open AccessReview

Nanoparticle-Integrated Hydrogels as Multifunctional Composite Materials for Biomedical Applications

1
Dipartimento di Farmacia, Università di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy
2
Istituto per i Polimeri Compositi e Biomateriali (IPCB-CNR), P.le Tecchio 80, 80125 Napoli, Italy
3
Dipartimento Scienze Chimiche e Tecnologie dei Materiali (DSCTM-CNR), P.le Aldo Moro 7, 00185 Roma, Italy
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Rolando Barbucci
Gels 2015, 1(2), 162-178; https://doi.org/10.3390/gels1020162
Received: 3 July 2015 / Revised: 25 September 2015 / Accepted: 28 September 2015 / Published: 14 October 2015
(This article belongs to the Special Issue Nanoparticle-Hydrogel Composites for Biomedical Applications)
This review focuses on the most recent developments in the field of nanocomposite hydrogels intended for biomedical applications. Nanocomposite hydrogels are hydrated polymeric networks with a physically or covalently crosslinked three-dimensional (3D) structure swollen with water, in the presence of nanoparticles or nanostructures. A wide array of nanomaterials (polymeric, carbon-based, metallic, ceramic) can be incorporated within the hydrogel network to obtain reinforced nanocomposite hydrogels. Nanocomposites represent a new class of materials with properties absent in the individual components. In particular, the incorporation of nanomaterials within a polymeric hydrogel network is an attractive approach to tailor the mechanical properties of the hydrogels and/or to provide the nanocomposite with responsiveness to external stimuli. View Full-Text
Keywords: nanocomposites; nanoparticles; hydrogels; biomedical applications; nanocomposite hydrogels nanocomposites; nanoparticles; hydrogels; biomedical applications; nanocomposite hydrogels
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MDPI and ACS Style

Biondi, M.; Borzacchiello, A.; Mayol, L.; Ambrosio, L. Nanoparticle-Integrated Hydrogels as Multifunctional Composite Materials for Biomedical Applications. Gels 2015, 1, 162-178.

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