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Article

Unveiling the Role Displayed by Penicillium digitatum PdMut3 Transcription Factor in Pathogen–Fruit Interaction

Instituto Valenciano de Investigaciones Agrarias (IVIA), Centro de Protección Vegetal y Biotecnología, 46113 Moncada, Spain
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Author to whom correspondence should be addressed.
Present Address: Food Biotechnology Department, Instituto de Agroquímica y Tecnología de Alimentos (IATA), Consejo Superior de Investigaciones Científicas (CSIC), Catedrático Agustín Escardino Benlloch 7, 46980 Paterna, Spain.
Academic Editor: Susanne Zeilinger
J. Fungi 2021, 7(10), 828; https://doi.org/10.3390/jof7100828
Received: 20 September 2021 / Revised: 29 September 2021 / Accepted: 30 September 2021 / Published: 3 October 2021
(This article belongs to the Special Issue Control of Postharvest Pathogenic Penicillium)
Zn2Cys6 transcription factors are unique to fungi and are involved in different regulatory functions. In this study, we have identified the Penicillium digitatumPdMut3 gene, which encodes a putative Zn (II) 2Cys6 DNA-binding protein. Elimination of PdMut3 in Pd1 strain caused increased virulence during citrus infection. The transcription of the PdMut3 gene showed a higher expression rate during fungal growth and less transcription during fruit infection. Furthermore, the deletion of the gene in the wild-type isolate of P. digitatum did not produce any modification of the sensitivity to different fungicides, indicating that the gene is not associated with resistance to fungicides. In contrast, PdMut3 null mutants showed a reduction in growth in minimal media, which was associated with severe alterations in conidiophore development and morphological alterations of the hyphae. Mutants showed greater sensitivity to compounds that interfere with the cell wall and an invasive growth block. Thus, PdMut3 might have an indirect role in fungi virulence through metabolism and peroxisomes development. View Full-Text
Keywords: citrus; fungicide resistance; Penicillium digitatum; postharvest; transcription factor; virulence; peroxisomes citrus; fungicide resistance; Penicillium digitatum; postharvest; transcription factor; virulence; peroxisomes
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MDPI and ACS Style

de Ramón-Carbonell, M.; Sánchez-Torres, P. Unveiling the Role Displayed by Penicillium digitatum PdMut3 Transcription Factor in Pathogen–Fruit Interaction. J. Fungi 2021, 7, 828. https://doi.org/10.3390/jof7100828

AMA Style

de Ramón-Carbonell M, Sánchez-Torres P. Unveiling the Role Displayed by Penicillium digitatum PdMut3 Transcription Factor in Pathogen–Fruit Interaction. Journal of Fungi. 2021; 7(10):828. https://doi.org/10.3390/jof7100828

Chicago/Turabian Style

de Ramón-Carbonell, Marta, and Paloma Sánchez-Torres. 2021. "Unveiling the Role Displayed by Penicillium digitatum PdMut3 Transcription Factor in Pathogen–Fruit Interaction" Journal of Fungi 7, no. 10: 828. https://doi.org/10.3390/jof7100828

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