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Onychomycosis: A Review

Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via Massarenti 1, 40138 Bologna, Italy
Author to whom correspondence should be addressed.
Academic Editor: Theodore Rosen
J. Fungi 2015, 1(1), 30-43;
Received: 28 February 2015 / Revised: 13 March 2015 / Accepted: 18 March 2015 / Published: 27 March 2015
(This article belongs to the Special Issue Cutaneous Fungal Diseases)
PDF [1093 KB, uploaded 27 March 2015]


Onychomycosis is the most common nail infective disorder. It is caused mainly by anthropophilic dermatophytes, in particular by Trichophyton rubrum and T. mentagrophytes var. interdigitale. Yeasts, like Candida albicans and C. parapsilosis, and molds, like Aspergillus spp., represent the second cause of onychomycosis. The clinical suspect of onychomycosis should be confirmed my mycology. Onychoscopy is a new method that can help the physician, as in onychomycosis, it shows a typical fringed proximal margin. Treatment is chosen depending on the modality of nail invasion, fungus species and the number of affected nails. Oral treatments are often limited by drug interactions, while topical antifungal lacquers have less efficacy. A combination of both oral and systemic treatment is often the best choice. View Full-Text
Keywords: onychomycosis; nail lacquers; systemic antifungal therapy; fungi; nail onychomycosis; nail lacquers; systemic antifungal therapy; fungi; nail

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Piraccini, B.M.; Alessandrini, A. Onychomycosis: A Review. J. Fungi 2015, 1, 30-43.

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