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Article

Predictors of Visceral Infectious Aneurysms in Patients with Infective Endocarditis and Systemic Embolization

by
Monique Boukobza
1,*,
Emila Ilic-Habensus
2,
Xavier Duval
2,3,4 and
Jean-Pierre Laissy
1,5
1
Department of Radiology, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, 75018 Paris, France
2
Clinical Investigation Center, Hopital Bichat–Claude-Bernard, Assistance Publique-Hôpitaux de Paris, 75018 Paris, France
3
INSERM Clinical Investigation Center 007, 75015 Paris, France
4
INSERM U738, Paris University, 75016 Paris, France
5
INSERM U1148, Paris University, 75018 Paris, France
*
Author to whom correspondence should be addressed.
J. Cardiovasc. Dev. Dis. 2025, 12(2), 57; https://doi.org/10.3390/jcdd12020057
Submission received: 14 December 2024 / Revised: 24 January 2025 / Accepted: 29 January 2025 / Published: 4 February 2025
(This article belongs to the Special Issue Current Practice in Cardiac Imaging)

Abstract

Background: To study whether infective endocarditis patients (IE-patients) with visceral embolic events (VEEs) at admission are at greater risk of developing visceral infectious aneurysms (VIAs) in left-sided infective endocarditis (LSIE) patients. Methods: We compared the data of prospectively collected 474 consecutive LSIE-patients (2005–2020) with and without VIAs. A whole-body-CTA was part of the initial work-up for all patients. Results: A total of 24 patients (5.1%) with VIA were included, of whom 19 (79.2%) had at least one VEE, compared to a proportion of 34% (p < 0.001) in IE-patients without VIAs. Both groups also differed in terms of vegetation size (>15 mm: 48% vs. 18%, p < 0.001), microorganisms, Streptococcus spp. (68.5% vs. 42%, p= 0.003), rare microorganisms (36% vs. 8.3%, p < 0.001) and concomitant extra-visceral infectious aneurysms (42% vs. 12.8%, p < 0.001). Cardiac surgery was performed in 21 patients (87.5%) and in-hospital mortality occurred in 2 (8%). Conclusions: This study shows a different profile of VIA–LSIE patients compared to LSIE-patients without. Streptococcus species were the most frequent causal agents. Our study indicates that the presence of VEEs in LSIE-patients could suggest an increased risk of VIA. This study also shows the need for further abdominal-CTA in all cases of left sided IE to detect asymptomatic visceral aneurysms.
Keywords: infective endocarditis; visceral embolic events; visceral infectious aneurysms; spleen infarct; kidney infarct infective endocarditis; visceral embolic events; visceral infectious aneurysms; spleen infarct; kidney infarct

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MDPI and ACS Style

Boukobza, M.; Ilic-Habensus, E.; Duval, X.; Laissy, J.-P. Predictors of Visceral Infectious Aneurysms in Patients with Infective Endocarditis and Systemic Embolization. J. Cardiovasc. Dev. Dis. 2025, 12, 57. https://doi.org/10.3390/jcdd12020057

AMA Style

Boukobza M, Ilic-Habensus E, Duval X, Laissy J-P. Predictors of Visceral Infectious Aneurysms in Patients with Infective Endocarditis and Systemic Embolization. Journal of Cardiovascular Development and Disease. 2025; 12(2):57. https://doi.org/10.3390/jcdd12020057

Chicago/Turabian Style

Boukobza, Monique, Emila Ilic-Habensus, Xavier Duval, and Jean-Pierre Laissy. 2025. "Predictors of Visceral Infectious Aneurysms in Patients with Infective Endocarditis and Systemic Embolization" Journal of Cardiovascular Development and Disease 12, no. 2: 57. https://doi.org/10.3390/jcdd12020057

APA Style

Boukobza, M., Ilic-Habensus, E., Duval, X., & Laissy, J.-P. (2025). Predictors of Visceral Infectious Aneurysms in Patients with Infective Endocarditis and Systemic Embolization. Journal of Cardiovascular Development and Disease, 12(2), 57. https://doi.org/10.3390/jcdd12020057

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