Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog
1
National Laboratory of Virology, Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary
2
Institute of Biology, Faculty of Sciences, University of Pécs, H-7624 Pécs, Hungary
3
Corden International Hungary Ltd., 1117 Budapest, Hungary
*
Author to whom correspondence should be addressed.
Academic Editor: Daniel Moura de Aguiar
Vet. Sci. 2021, 8(4), 61; https://doi.org/10.3390/vetsci8040061
Received: 1 March 2021
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Revised: 31 March 2021
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Accepted: 9 April 2021
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Published: 11 April 2021
Canine distemper virus (CDV) is a major viral pathogen in domestic dogs, belonging to the Paramyxoviridae family, in the Morbillivirus genus. It is present worldwide, and a wide range of domestic animals and wild carnivores are at risk. In the absence of vaccination, dogs have a low chance of survival; however, if and when a dog survives, it can take an average of a few weeks to a few months to fully wipe out the virus. In the present study, we traced the course of infection of a 1-year-old mixed-breed male dog. The animal had an unusually long course of persistent CDV infection with a vector-borne heartworm (Dirofilaria immitis) co-infection. The dog excreted the CDV for 17 months with PCR positivity in urine samples collected from February 2019 through June 2020. The sequencing and phylogenetic analysis of the hemagglutinin gene revealed the CDV to be the member of the endemic Arctic-like genetic lineage. To the best of our knowledge, this report represents the longest documented canine infection of CDV. Notably, we highlight the necessity regarding CDV infectivity studies to better comprehend the transmission attributes of the virus.
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Keywords:
Paramyxoviridae; Morbillivirus; canine distemper virus; haemagglutinin gene; arctic-like lineage; domestic dog; shelter; heartworm; Dirofilaria immitis
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MDPI and ACS Style
Lanszki, Z.; Zana, B.; Zeghbib, S.; Jakab, F.; Szabó, N.; Kemenesi, G. Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog. Vet. Sci. 2021, 8, 61. https://doi.org/10.3390/vetsci8040061
AMA Style
Lanszki Z, Zana B, Zeghbib S, Jakab F, Szabó N, Kemenesi G. Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog. Veterinary Sciences. 2021; 8(4):61. https://doi.org/10.3390/vetsci8040061
Chicago/Turabian StyleLanszki, Zsófia, Brigitta Zana, Safia Zeghbib, Ferenc Jakab, Nikoletta Szabó, and Gábor Kemenesi. 2021. "Prolonged Infection of Canine Distemper Virus in a Mixed-Breed Dog" Veterinary Sciences 8, no. 4: 61. https://doi.org/10.3390/vetsci8040061
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