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Vet. Sci. 2018, 5(1), 10; https://doi.org/10.3390/vetsci5010010

A Multicentric T-Cell Lymphoma with a Plasmacytoid Morphology in a Dog

1
The School of Veterinary Medicine, University of the West Indies, Saint Augustine, Trinidad and Tobago
2
Veterinary Diagnostic Laboratory, Ministry of Agriculture, Land and Fisheries, Eric Williams Medical Sciences Complex, Uriah Butler Highway, Mt Hope, Trinidad and Tobago
*
Author to whom correspondence should be addressed.
Received: 2 November 2017 / Revised: 15 January 2018 / Accepted: 18 January 2018 / Published: 20 January 2018
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Abstract

An 8-year-old male (neutered) Labrador with a history of erythematous skin lesions and exercise intolerance for a prolonged period was suddenly found dead. Necropsy findings revealed an infiltrative, focally extensive mass which occupied 25% of the cardiac interventricular septum. Severe endocardiosis was also found on the bicuspid and tricuspid valves. The submandibular lymph nodes and kidneys were bilaterally enlarged, and the pre-hepatic lymph node and spleen were also enlarged. Multiple dermal pustules were present around the mouth and on the ear, and small ulcers were present on the tongue. Histopathological examination detected the presence of neoplastic lymphocytes with a plasmacytoid morphology in these tissues as well as in the tongue and skin lesions. Immunohistochemical (CD3+/CD18+) evaluation was consistent with a T-cell lymphoma, which could be classified as a peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). View Full-Text
Keywords: plasmacytoid morphology; T-cell lymphoma; canine; pathology; immunohistochemistry; multicentric plasmacytoid morphology; T-cell lymphoma; canine; pathology; immunohistochemistry; multicentric
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Bally, A.; Acevedo, K.F.; Pargass, I.; Gyan, L.; Rajh, S.; Suepaul, R. A Multicentric T-Cell Lymphoma with a Plasmacytoid Morphology in a Dog. Vet. Sci. 2018, 5, 10.

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