Natural Biomaterials and Their Use as Bioinks for Printing Tissues
1
Department of Mechanical Engineering, University of Victoria, Victoria, BC V8P 5C2, Canada
2
Biomedical Engineering Program, University of Victoria, Victoria, BC V8P 5C2, Canada
3
Department of Chemistry, University of Victoria, Victoria, BC V8P 5C2, Canada
4
Division of Medical Sciences, University of Victoria, Victoria, BC V8P 5C2, Canada
*
Author to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Academic Editor: Houman Savoji
Bioengineering 2021, 8(2), 27; https://doi.org/10.3390/bioengineering8020027
Received: 30 January 2021
/
Revised: 12 February 2021
/
Accepted: 17 February 2021
/
Published: 20 February 2021
(This article belongs to the Special Issue 3D Bioprinting for Tissue Engineering and Regenerative Medicine)
The most prevalent form of bioprinting—extrusion bioprinting—can generate structures from a diverse range of materials and viscosities. It can create personalized tissues that aid in drug testing and cancer research when used in combination with natural bioinks. This paper reviews natural bioinks and their properties and functions in hard and soft tissue engineering applications. It discusses agarose, alginate, cellulose, chitosan, collagen, decellularized extracellular matrix, dextran, fibrin, gelatin, gellan gum, hyaluronic acid, Matrigel, and silk. Multi-component bioinks are considered as a way to address the shortfalls of individual biomaterials. The mechanical, rheological, and cross-linking properties along with the cytocompatibility, cell viability, and printability of the bioinks are detailed as well. Future avenues for research into natural bioinks are then presented.
View Full-Text
Keywords:
bioink; 3D bioprinting; biomaterials; tissue engineering; regenerative medicine
▼
Show Figures
Figure 1
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
MDPI and ACS Style
Benwood, C.; Chrenek, J.; Kirsch, R.L.; Masri, N.Z.; Richards, H.; Teetzen, K.; Willerth, S.M. Natural Biomaterials and Their Use as Bioinks for Printing Tissues. Bioengineering 2021, 8, 27. https://doi.org/10.3390/bioengineering8020027
AMA Style
Benwood C, Chrenek J, Kirsch RL, Masri NZ, Richards H, Teetzen K, Willerth SM. Natural Biomaterials and Their Use as Bioinks for Printing Tissues. Bioengineering. 2021; 8(2):27. https://doi.org/10.3390/bioengineering8020027
Chicago/Turabian StyleBenwood, Claire, Josie Chrenek, Rebecca L. Kirsch, Nadia Z. Masri, Hannah Richards, Kyra Teetzen, and Stephanie M. Willerth. 2021. "Natural Biomaterials and Their Use as Bioinks for Printing Tissues" Bioengineering 8, no. 2: 27. https://doi.org/10.3390/bioengineering8020027
Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
