Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design
2.1.1. Inclusion Criteria
2.1.2. Exclusion Criteria
2.2. Ethics Committee Approval
2.3. Calibration of Examiners and Classification Criteria
2.4. Clinical Procedure
Endodontic Instrumentation
2.5. Clinical and Radiographic Follow-Up
3. Results
4. Discussion
5. Conclusions
6. Future Research Directions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Sealer | Variable | N | Min | Max | Mean | SD | p-Value |
---|---|---|---|---|---|---|---|
AH | Pain 24 h | 36 | 0 | 10 | 0.97 | 2.27 | <0.001 |
Pain 48 h | 8 | 0.53 | 1.61 | <0.001 | |||
Pain 7 days | 3 | 0.17 | 0.56 | <0.001 | |||
NEO | Pain 24 h | 34 | 0 | 2 | 0.06 | 0.34 | <0.001 |
Pain 48 h | 1 | 0.03 | 0.17 | <0.001 | |||
Pain 7 days | 0 | 0.0 | 0.0 | <0.001 |
Variable | Statistic | p-Value |
---|---|---|
Pain 24 h | 764.0 | 0.005 ** (AH > NEO) |
Pain 48 h | 697.5 | 0.055 |
Pain 7 days | 680.0 | 0.049 * (AH > NEO) |
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Algar, J.; Docampo-Vázquez, C.; Rico-Romano, C.; Boquete-Castro, A.; Obispo-Díaz, C.; Aragoneses, J.M. Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions. Bioengineering 2025, 12, 376. https://doi.org/10.3390/bioengineering12040376
Algar J, Docampo-Vázquez C, Rico-Romano C, Boquete-Castro A, Obispo-Díaz C, Aragoneses JM. Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions. Bioengineering. 2025; 12(4):376. https://doi.org/10.3390/bioengineering12040376
Chicago/Turabian StyleAlgar, Juan, Cristian Docampo-Vázquez, Cristina Rico-Romano, Ana Boquete-Castro, Cristina Obispo-Díaz, and Juan Manuel Aragoneses. 2025. "Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions" Bioengineering 12, no. 4: 376. https://doi.org/10.3390/bioengineering12040376
APA StyleAlgar, J., Docampo-Vázquez, C., Rico-Romano, C., Boquete-Castro, A., Obispo-Díaz, C., & Aragoneses, J. M. (2025). Randomised Clinical Trial: Effect of AH Plus and Neosealer Flo on Postoperative Pain and Healing of Periapical Lesions. Bioengineering, 12(4), 376. https://doi.org/10.3390/bioengineering12040376