Functional Near-Infrared Spectroscopy-Based Evidence of the Cerebral Oxygenation and Network Characteristics of Upper Limb Fatigue
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Procedures
2.3. Functional Near-Infrared Spectroscopy System Acquisition
2.4. Data Pre-Processing
2.5. Functional Connectivity Analysis
2.6. Statistical Analysis
3. Results
3.1. Cerebral Oxygenation Changes
3.2. Functional Connectivity Changes
3.3. Physiological Response to Fatigue
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Area | Channel | Pre-Resting (×10−4 mmol/L) | Post-Resting (×10−4 mmol/L) | T | p |
---|---|---|---|---|---|
Orbitofrontal area | Ch1 | 0.53 ± 4.57 | 14.24 ± 12.41 | −5.1650 | <0.001 |
Ch2 | −0.46 ± 3.75 | −14.22 ± 12.97 | −4.9246 | <0.001 | |
Ch4 | 0.17 ± 3.10 | −5.87 ± 7.40 | −3.1858 | 0.005 | |
Ch7 | 0.01 ± 3.40 | −8.71 ± 10.83 | −3.1562 | 0.006 | |
Frontopolar area | Ch3 | −0.08 ± 3.17 | −6.46 ± 9.86 | −2.5924 | 0.019 |
Ch5 | 0.60 ± 3.21 | −3.74 ± 3.48 | −3.9272 | 0.001 | |
Ch8 | 0.10 ± 2.97 | −6.62 ± 6.39 | −3.9427 | 0.001 | |
Dorsolateral prefrontal cortex | Ch6 | 0.16 ± 3.24 | −3.81 ± 5.50 | −2.6980 | 0.015 |
Ch9 | 0.40 ± 1.92 | −6.89 ± 7.04 | −4.0708 | 0.001 | |
Ch13 | 0.56 ± 4.31 | −6.05 ± 11.03 | −2.4281 | 0.027 | |
Ch14 | 0.53 ± 3.35 | −3.30 ± 5.65 | −2.7408 | 0.014 | |
Ch17 | 3.16 ± 9.84 | −7.24 ± 9.30 | −2.4574 | 0.025 | |
Ventrolateral prefrontal cortex | Ch18 | 2.13 ± 6.80 | −3.43 ± 7.69 | −2.9275 | 0.009 |
Ch32 | 11.44 ± 37.49 | −8.60 ± 29.87 | −2.1332 | 0.048 | |
Includes Frontal eye fields | Ch16 | −0.41 ± 5.05 | −7.16 ± 13.41 | −2.1850 | 0.043 |
Ch23 | 0.73 ± 3.91 | −5.50 ± 9.19 | −3.6556 | 0.002 | |
Pre-Motor and Supplementary Motor Cortex | Ch26 | 2.08 ± 4.22 | −4.52 ± 6.43 | −3.7644 | 0.002 |
Ch28 | 0.29 ± 8.68 | −4.59 ± 7.64 | −2.6413 | 0.017 | |
Ch39 | 1.28 ± 4.93 | −3.42 ± 7.13 | −2.1521 | 0.046 | |
Ch41 | 0.76 ± 5.94 | −3.33 ± 6.66 | −3.1625 | 0.006 | |
Primary Motor Cortex | Ch40 | 0.56 ± 3.34 | −2.07 ± 6.22 | −2.3963 | 0.028 |
Primary Somatosensory Cortex | Ch46 | 1.01 ± 3.65 | −1.98 ± 4.19 | −2.2490 | 0.038 |
Ch50 | 0.17 ± 4.11 | −3.32 ± 4.03 | −2.4860 | 0.024 |
Region-Region | T-Value | p-Value | |
---|---|---|---|
PM&SMA_L | VLPFC_L | −4.221 | <0.001 |
PM&SMA_L | DLPFC_L | −4.27 | <0.001 |
PM&SMA_L | DLPFC_R | −4.3057 | <0.001 |
PM&SMA_L | VLPFC_R | −4.3882 | <0.001 |
PM&SMA_L | VLPFC_R | −4.2824 | <0.001 |
PM&SMA_L | SAC_R | −4.3782 | <0.001 |
PM&SMA_L | DLPFC_M | −3.9482 | <0.001 |
PM&SMA_R | OFA_L | −5.8336 | <0.001 |
PM&SMA_R | FPA_L | −3.9229 | <0.001 |
PM&SMA_R | FPA_L | −4.9266 | <0.001 |
PM&SMA_R | DLPFC_L | −4.549 | <0.001 |
PM&SMA_R | DLPFC_L | −4.3457 | <0.001 |
PM&SMA_R | S1_L | −4.0253 | <0.001 |
PM&SMA_R | DLPFC_R | −4.1395 | <0.001 |
PM&SMA_R | VLPFC_R | −4.2891 | <0.001 |
PM&SMA_R | VLPFC_R | −4.5104 | <0.001 |
PM&SMA_R | S1_R | −3.9672 | <0.001 |
M1_L | DLPFC_M | −3.9406 | <0.001 |
M1_R | OFA_L | −5.3158 | <0.001 |
M1_R | FPA_L | −4.3207 | <0.001 |
M1_R | DLPFC_L | −5.3984 | <0.001 |
M1_R | OFA_R | −3.9362 | <0.001 |
M1_R | DLPFC_R | −4.1346 | <0.001 |
M1_R | VLPFC_R | −5.4862 | <0.001 |
M1_R | VLPFC_R | −4.7553 | <0.001 |
M1_R | DLPFC_M | −4.524 | <0.001 |
M1_M | OFA_L | −4.5653 | <0.001 |
M1_M | DLPFC_L | −3.9048 | <0.001 |
M1_M | DLPFC_R | −3.9669 | <0.001 |
M1_M | VLPFC_R | −5.1262 | <0.001 |
M1_M | VLPFC_R | −5.0606 | <0.001 |
DLPFC_L | DLPFC_L | −4.267 | <0.001 |
DLPFC_L | VLPFC_R | −4.8204 | <0.001 |
DLPFC_M | FPA_R | −4.2324 | <0.001 |
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Li, F.; Bi, J.; Liang, Z.; Li, L.; Liu, Y.; Huang, L. Functional Near-Infrared Spectroscopy-Based Evidence of the Cerebral Oxygenation and Network Characteristics of Upper Limb Fatigue. Bioengineering 2023, 10, 1112. https://doi.org/10.3390/bioengineering10101112
Li F, Bi J, Liang Z, Li L, Liu Y, Huang L. Functional Near-Infrared Spectroscopy-Based Evidence of the Cerebral Oxygenation and Network Characteristics of Upper Limb Fatigue. Bioengineering. 2023; 10(10):1112. https://doi.org/10.3390/bioengineering10101112
Chicago/Turabian StyleLi, Feng, Jiawei Bi, Zhiqiang Liang, Lu Li, Yu Liu, and Lingyan Huang. 2023. "Functional Near-Infrared Spectroscopy-Based Evidence of the Cerebral Oxygenation and Network Characteristics of Upper Limb Fatigue" Bioengineering 10, no. 10: 1112. https://doi.org/10.3390/bioengineering10101112