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Nanoemulsions of Essential Oils: New Tool for Control of Vector-Borne Diseases and In Vitro Effects on Some Parasitic Agents

1
Facultad de Química y Biología, Universidad de Santiago de Chile, Casilla 40, Correo 33, Santiago 9170022, Chile
2
Laboratório de Tecnologia em Produtos Naturais, Universidade Federal Fluminense, Niterói 24241-002, Brazil
*
Authors to whom correspondence should be addressed.
Medicines 2019, 6(2), 42; https://doi.org/10.3390/medicines6020042
Received: 31 January 2019 / Revised: 18 March 2019 / Accepted: 19 March 2019 / Published: 27 March 2019
(This article belongs to the Special Issue Biological Potential and Medical Use of Secondary Metabolites)
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Abstract

The control of infectious/parasitic diseases is a continuing challenge for global health, which in turn requires new methods of action and the development of innovative agents to be used in its prevention and/or treatment. In this context, the control of vectors and intermediate hosts of etiological agents is an efficient method in the prevention of human and veterinary diseases. In later stages, it is necessary to have bioactive compounds that act efficiently on the agents that produce the disease. However, several synthetic agents have strong residual effects in humans and other animals and cause environmental toxicity, affecting fauna, flora and unbalancing the local ecosystem. Many studies have reported the dual activity of the essential oils (EOs): (i) control of vectors that are important in the cycle of disease transmission, and (ii) relevant activity against pathogens. In general, EOs have an easier degradation and cause less extension of environmental contamination. However, problems related to solubility and stability lead to the development of efficient vehicles for formulations containing EOs, such as nanoemulsions. Therefore, this systematic review describes several studies performed with nanoemulsions as carriers of EOs that have larvicidal, insecticidal, repellent, acaricidal and antiparasitic activities, and thus can be considered as alternatives in the vector control of infectious and parasitic diseases, as well as in the combat against etiological agents of parasitic origin. View Full-Text
Keywords: nanoemulsion; essential oils; vector control; infectious diseases nanoemulsion; essential oils; vector control; infectious diseases
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Echeverría, J.; Albuquerque, R.D.D.G. Nanoemulsions of Essential Oils: New Tool for Control of Vector-Borne Diseases and In Vitro Effects on Some Parasitic Agents. Medicines 2019, 6, 42.

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