Antioxidant and Antimicrobial Activities of the Essential Oil of Achillea millefolium L. Grown in France
Laboratoire de Chimie Agro-Industrielle, Université Fédérale de Toulouse Midi-Pyrénées, INP-ENSIACET, Toulouse 31030, France
Unité Mixte 134 Processus Infectieux en Milieu Insulaire Tropical, Université de la Réunion, INSERM U1187, CNRS UMR 9192, IRD UMR 249. Plateforme Technologique CYROI, Sainte Clotilde 97490, France
Department of Food Technology, Kaunas University of Technology, Radvilènu pl. 19, LT-50254 Kaunas, Lithuania
Laboratoires Agronutrition SAS, 3 allée de l’Orchidée Carbone 31390, France
Author to whom correspondence should be addressed.
Academic Editor: Eleni Skaltsa
Medicines 2017, 4(2), 30; https://doi.org/10.3390/medicines4020030
Received: 20 February 2017 / Revised: 27 April 2017 / Accepted: 15 May 2017 / Published: 19 May 2017
(This article belongs to the Special Issue Antimicrobial, Antioxidant and Anti-inflammatory Activities of Essential Oils)
Background: This study aimed to examine the composition of essential oil (EO) of A. millefolium aerial parts wild plant grown in France and evaluate its antioxidant, antibacterial, and antifungal activities. Methods: GC-MS was used to identify the chemical composition of EO. Antioxidant activity (AA) of EO was evaluated by Oxipres method. Antimicrobial activity of EO was evaluated by Agar-well diffusion and a broth microdilution assay. Results: Forty-three volatile compounds were identified. Major compounds were camphor (12.8%), germacrene-D (12%), (E)-nerolidol (7.3%), sabinene (6.7%), (E)-p-mentha-2,8-dien-1-ol (4.5%), and 1,8-cineole (4%). EO shows strong AA against Sunflower oil oxidation. Additionally, an inhibitory effect against microbial organisms (bacteria and fungi) was found. Conclusion: The EO composition of A. millefolium chemotype located in France was studied. The EO of the A. millefolium wild plant grown in France is quite an effective antioxidant in sunflower oil oxidation; it also possesses inhibitory effects against famous bacteria and fungi.