Next Article in Journal / Special Issue
Assessment of Health Risk in Human Populations Due to Chlorpyrifos
Previous Article in Journal
The Chemistry and Toxicology of Depleted Uranium
Previous Article in Special Issue
Risk Mitigation Measures: An Important Aspect of the Environmental Risk Assessment of Pharmaceuticals
Open AccessReview

Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles

Department of Environment, University of the Aegean, Mytilene 81100, Greece
Faculty of Applied Sciences, Delft University of Technology, Delft 2628BL, The Netherlands
Authors to whom correspondence should be addressed.
Toxics 2014, 2(1), 79-91;
Received: 3 January 2014 / Revised: 5 March 2014 / Accepted: 11 March 2014 / Published: 19 March 2014
(This article belongs to the Special Issue Risk Assessment of Environmental Contaminants)
PDF [435 KB, uploaded 19 March 2014]


The increasing penetration of materials and products containing engineered nanoparticles (ENPs) to the market is posing many concerns regarding their environmental impacts. To assess these impacts, there is an urgent need of techniques for determining the health-related properties of ENPs and standards for assessing their toxicity. Although a wide number of systems for characterizing nanoparticles in different media (i.e., gases and liquids) is already commercially available, the development of protocols for determining the cytotoxicity of ENPs is still at an infant stage, drawing upon existing knowledge from general toxicology. In this regard, differences in the preparation of ENP-containing solutions for cytotoxicity testing, as well as in the steps involved in the tests can result in significant deviations and inconsistencies between studies. In an attempt to highlight the urgent need for assessing the environmental impacts of nanotechnology, this article provides a brief overview of the existing methods for determining health-related properties of ENPs and their cytotoxicity. View Full-Text
Keywords: nanotechnology; engineered nanoparticles; cytotoxicity; human exposure nanotechnology; engineered nanoparticles; cytotoxicity; human exposure
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Kalantzi, O.-I.; Biskos, G. Methods for Assessing Basic Particle Properties and Cytotoxicity of Engineered Nanoparticles. Toxics 2014, 2, 79-91.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Toxics EISSN 2305-6304 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top