The Importance of Alliance between Hematologists and Dentists: A Retrospective Study on the Development of Bisphosphonates Osteonecrosis of the Jaws (Bronj) in Multiple Myeloma Patients
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
- Rajkumar, S.V. Multiple myeloma: 2011 update on diagnosis, risk-stratification, and management. Am. J. Hematol. 2011, 86, 57–65. [Google Scholar] [CrossRef] [PubMed]
- Nofsinger, Y.C.; Mirza, N.; Rowan, P.T.; Lanza, D.; Weinstein, G. Head and neck manifestations of plasma cell neoplasms. Laryngoscope 1997, 107, 741–746. [Google Scholar] [CrossRef]
- Batsakis, J.G.; Medeiros, J.L.; Luna, M.A.; El-Naggar, A.K. Plasma cell dyscrasias and the head and neck. Ann. Diagn. Pathol. 2002, 6, 129–140. [Google Scholar] [CrossRef] [PubMed]
- Available online: http://www.airc.it/tumori/mieloma-multiplo.asp (accessed on 25 February 2016).
- Raab, M.S.; Podar, K.; Breitkreutz, I. Multiple myeloma. Lancet 2009, 374, 324–339. [Google Scholar] [CrossRef]
- Terpos, E.; Sezer, O.; Croucher, P.I. The use of bisphosphonates in mul-tiple myeloma: Recommendations of an expert panel on behalf of the Eu-ropean Myeloma Network. Ann. Oncol. 2009, 20, 1303–1317. [Google Scholar] [CrossRef] [PubMed]
- Neville, B.W. Hematologic disorders. In Oral and Maxillofacial Pathology, 3rd ed.; Neville, B.W., Damm, D.D., Allen, C.M., Bouquot, J.E., Eds.; Saunders-Elsevier: Philadelphia, PA, USA, 2009; pp. 526–528. [Google Scholar]
- Stashenko, P.; Dewhirst, F.E.; Peros, W.J. Synergistic interactions between interleukin 1, tumor necrosis factor, and lymphotoxin in bone resorption. J. Immunol. 1987, 138, 1464–1468. [Google Scholar] [PubMed]
- Xiaoxue, W.; Xiaojing, Y.; Yan, L. A meta-analysis of the antitumor effect and safety of bisphosphonates in the treatment of multiple myeloma. Int. J. Clin. Exp. Med. 2015, 8, 6743–6754. [Google Scholar]
- Mhaskar, R.; Redzepovic, J.; Wheatley, K.; Clark, O.A.C.; Miladinovic, B.; Glasmacher, A.; Kumar, A.; Djulbegovic, B. Bisphosphonates in multiple myeloma: A network meta-analysis (Review). Cochrane Libr. 2017, 12, CD003188. [Google Scholar] [CrossRef]
- Morgan, G.J.; Davies, F.E.; Gregory, W.M. First-line treatment with zoledronic acid as compared with clodronic acid in multiple (MRC Myeloma IX): A randomized controlled trial. Lancet 2010, 376, 1989–1999. [Google Scholar] [CrossRef]
- Pozzi, S.; Raje, N. The Role of Bisphosphonates in Multiple Myeloma: Mechanisms, Side Effects, and the Future. Oncologist 2011, 16, 651–666. [Google Scholar] [CrossRef]
- Cerrato, A.; Zanette, G.; Boccuto, M.; Angelini, A.; Valente, M.; Bacci, C. Actinomyces and MRONJ: A retrospective study and a literature review. J. Stomatol. Oral Maxillofac. Surg. 2020, in press. [Google Scholar] [CrossRef] [PubMed]
- Allen, M.R.; Burr, D.B. The pathogenesis of bisphosphonate-related osteo- necrosis of the jaw: So many hypotheses, so few data. J. Oral Maxillofac. Surg. 2009, 67, 61–70. [Google Scholar] [CrossRef] [PubMed]
- Mavrokokki, T.; Cheng, A.; Stein, B.; Goss, A. Nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in Australia. J. Oral Maxillofac. Surg. 2007, 65, 415–423. [Google Scholar] [CrossRef]
- Gliklich, R.; Wilson, J. Epidemiology of bisphosphonate-related osteonecrosis of the jaws: The utility of a national registry. J. Oral Maxillofac. Surg. 2009, 67, 71–74. [Google Scholar] [CrossRef]
- Assaf, A.T.; Smeets, R.; Riecke, B. Incidence of Bisphosphonate-related Osteonecrosis of the Jaw in Consideration of Primary Diseases and Concomitant Therapies. Anticancer Res. 2013, 33, 3917–3924. [Google Scholar] [PubMed]
- Bamias, A.; Kastritis, E.; Bamia, C. Osteonecrosis of the jaw in cancer after treatment with bisphosphonates: Incidence and risk factors. J. Clin. Oncol. 2005, 23, 8580–8587. [Google Scholar] [CrossRef]
- Boonyapakorn, T.; Schirmer, I.; Reichart, P.A. Bisphosphonate-induced osteonecrosis of the jaws: Prospective study of 80 patients with multiple myeloma and other malignancies. Oral Oncol. 2008, 44, 857–859. [Google Scholar] [CrossRef]
- Durie, B.G.; Katz, M.; Crowley, J. Osteonecrosis of the jaw and bisphosphonates. N. Engl. J. Med. 2005, 353, 99–102. [Google Scholar]
- Woo, S.B.; Hellstein, J.W.; Kalmar, J.R. Narrative [corrected] review: Bisphosphonates and osteonecrosis of the jaws. Ann. Intern. Med. 2006, 144, 753–761. [Google Scholar] [CrossRef]
- Vahtsevanos, K.; Kyrgidis, A.; Verrou, E. Longitudinal cohort study of risk factors in cancer patients of bisphosphonate-related osteonecrosis of the jaw. J. Clin. Oncol. 2009, 27, 5356–5362. [Google Scholar] [CrossRef]
- Fusco, V.; Galassi, C.; Berruti, A. Osteonecrosis of the Jaw After Zoledronic Acid and Denosumab Treatment. J. Clin. Oncol. 2011, 29, e521–e522. [Google Scholar] [CrossRef] [PubMed]
- Del Conte, A.; Bernardeschi, P.; La Ferla, F. Bisphosphonate-induced osteonecrosis of the jaw 32 months after interruption of zoledronate in a patient with multiple myeloma. J. Oral Maxillofac. Surg. 2010, 68, 1179–1182. [Google Scholar] [CrossRef] [PubMed]
- Dimopoulos, M.A.; Kastritis, E.; Bamia, C. Reduction of osteonecrosis of the jaw (ONJ) after implementation of preventive measures in patients with multiple myeloma treated with zoledronic acid. Ann. Oncol. 2009, 20, 117. [Google Scholar] [CrossRef]
- Montefusco, V.; Gay, F.; Spina, F. Antibiotic prophylaxis before dental procedures can reduce ONJ incidence. ASH Annu. Meet. Abstr. 2007, 110, 3613. [Google Scholar] [CrossRef]
- Borrell, L.N.; Papapanou, P.N. Analytical epidemiology of periodontitis. J. Clin. Periodontol. 2005, 32, 132–158. [Google Scholar] [CrossRef]
- Ficarra, G.; Beninati, F.; Rubino, I. Osteonecrosis of the jaws in periodontal patients with a history of bisphosphonates treatment. J. Clin. Periodontol. 2005, 32, 1123–1128. [Google Scholar] [CrossRef]
- Di Fede, O.; Panzarella, V.; Mauceri, R. The dental management of patients at risk of medication-related osteonecrosis of the jaw: New paradigm of primary prevention. BioMed Res. Int. 2018, 2018, 2684924. [Google Scholar] [CrossRef]
- Weitzman, R.; Sauter, N.; Eriksen, E.F. Critical review: Updated reccomendations for the prevention, diagnosis and treatment of osteonecrosis of the jaw in cancer patients. Crit. Rev. Oncol./Hematol. 2007, 62, 148–162. [Google Scholar] [CrossRef]
- Aldhalaan, N.A.; Baqais, A.; Al-Omar, A. Medication-related Osteonecrosis of the Jaw: A review. Cureus 2020, 12, e6944. [Google Scholar] [CrossRef]
- Cardoso, C.S.; Gerngross, P.J.; Hofstede, T.M. The multiple oral presentations of multiple myeloma. Supportive Care Cancer 2014, 22, 259–267. [Google Scholar] [CrossRef]
- Badros, A.; Weikel, D.; Salama, A. Osteonecrosis of the Jaw in Multiple Myeloma Patients: Clinical Features and Risk Factors. J. Clin. Oncol. 2006, 24, 945–952. [Google Scholar] [CrossRef] [PubMed]
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Bacci, C.; Cerrato, A.; Dotto, V.; Zambello, R.; Barilà, G.; Liço, A.; Semenzato, G.; Stellini, E.; Zanette, G. The Importance of Alliance between Hematologists and Dentists: A Retrospective Study on the Development of Bisphosphonates Osteonecrosis of the Jaws (Bronj) in Multiple Myeloma Patients. Dent. J. 2021, 9, 11. https://doi.org/10.3390/dj9020011
Bacci C, Cerrato A, Dotto V, Zambello R, Barilà G, Liço A, Semenzato G, Stellini E, Zanette G. The Importance of Alliance between Hematologists and Dentists: A Retrospective Study on the Development of Bisphosphonates Osteonecrosis of the Jaws (Bronj) in Multiple Myeloma Patients. Dentistry Journal. 2021; 9(2):11. https://doi.org/10.3390/dj9020011
Chicago/Turabian StyleBacci, Christian, Alessia Cerrato, Virginia Dotto, Renato Zambello, Gregorio Barilà, Albana Liço, Gianpietro Semenzato, Edoardo Stellini, and Gastone Zanette. 2021. "The Importance of Alliance between Hematologists and Dentists: A Retrospective Study on the Development of Bisphosphonates Osteonecrosis of the Jaws (Bronj) in Multiple Myeloma Patients" Dentistry Journal 9, no. 2: 11. https://doi.org/10.3390/dj9020011
APA StyleBacci, C., Cerrato, A., Dotto, V., Zambello, R., Barilà, G., Liço, A., Semenzato, G., Stellini, E., & Zanette, G. (2021). The Importance of Alliance between Hematologists and Dentists: A Retrospective Study on the Development of Bisphosphonates Osteonecrosis of the Jaws (Bronj) in Multiple Myeloma Patients. Dentistry Journal, 9(2), 11. https://doi.org/10.3390/dj9020011