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Inorganics 2015, 3(2), 139-154;

Gilded Hope for Medicine

Department of Chemistry, University of Sharjah, Sharjah 27272, United Arab Emirates
Department of Chemistry, Blinn College, Bryan, TX 77805, USA
Department of Chemistry, Delaware State University, 1200 N. DuPont Highway, Dover, DE, USA
Author to whom correspondence should be addressed.
Academic Editor: Antonio Laguna
Received: 30 January 2015 / Revised: 13 April 2015 / Accepted: 15 April 2015 / Published: 15 May 2015
(This article belongs to the Special Issue Frontiers in Gold Chemistry)
Full-Text   |   PDF [2335 KB, uploaded 15 May 2015]   |  


Gold is emerging as a potential therapeutic agent in the treatment of arthritis, cancer and AIDS. The therapeutic mechanism of arthritic gold drugs and their modification in the presence of stomach hydrochloric acid, in the joints, and in the presence of mild and strong oxidizing agents is a matter of debate. It is believed that gold affects the entire immune response and reduces its potency and limits its oxidizing nature. DNA apparently is not the main target of gold in cancer treatment. Rheumatoid arthritis, cancer, heart diseases and recently AIDS have all been targeted with gold nanoparticles therapy. The era of gold nanoparticles started with cancer imaging and treatment studies. Gold nanoparticles have emerged as smart drug vehicles. View Full-Text
Keywords: gold drugs; gold nanoparticles; rheumatoid arthritis; chrysotherapy; cancer; HIV gold drugs; gold nanoparticles; rheumatoid arthritis; chrysotherapy; cancer; HIV

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Naggar, M.E.; Shehadi, I.; Abdou, H.E.; Mohamed, A.A. Gilded Hope for Medicine. Inorganics 2015, 3, 139-154.

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