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Open AccessFeature PaperArticle

Impact of a New SARS-CoV-2 Variant on the Population: A Mathematical Modeling Approach

Department of Mathematics, New Mexico Tech, Socorro, NM 87801, USA
Instituto Universitario de Matemática Multidisciplinar, Universitat Politècnica de València, Camí de Vera, s/n, 46022 València, Spain
Author to whom correspondence should be addressed.
Academic Editor: Cristiana J. Silva
Math. Comput. Appl. 2021, 26(2), 25;
Received: 20 February 2021 / Revised: 24 March 2021 / Accepted: 25 March 2021 / Published: 27 March 2021
(This article belongs to the Collection Mathematical Modelling of COVID-19)
Several SARS-CoV-2 variants have emerged around the world, and the appearance of other variants depends on many factors. These new variants might have different characteristics that can affect the transmissibility and death rate. The administration of vaccines against the coronavirus disease 2019 (COVID-19) started in early December of 2020 and in some countries the vaccines will not soon be widely available. For this article, we studied the impact of a new more transmissible SARS-CoV-2 strain on prevalence, hospitalizations, and deaths related to the SARS-CoV-2 virus. We studied different scenarios regarding the transmissibility in order to provide a scientific support for public health policies and bring awareness of potential future situations related to the COVID-19 pandemic. We constructed a compartmental mathematical model based on differential equations to study these different scenarios. In this way, we are able to understand how a new, more infectious strain of the virus can impact the dynamics of the COVID-19 pandemic. We studied several metrics related to the possible outcomes of the COVID-19 pandemic in order to assess the impact of a higher transmissibility of a new SARS-CoV-2 strain on these metrics. We found that, even if the new variant has the same death rate, its high transmissibility can increase the number of infected people, those hospitalized, and deaths. The simulation results show that health institutions need to focus on increasing non-pharmaceutical interventions and the pace of vaccine inoculation since a new variant with higher transmissibility, such as, for example, VOC-202012/01 of lineage B.1.1.7, may cause more devastating outcomes in the population. View Full-Text
Keywords: SARS-CoV-2 variant; mutation; scenarios; mathematical modeling; simulation SARS-CoV-2 variant; mutation; scenarios; mathematical modeling; simulation
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MDPI and ACS Style

Gonzalez-Parra, G.; Martínez-Rodríguez, D.; Villanueva-Micó, R.J. Impact of a New SARS-CoV-2 Variant on the Population: A Mathematical Modeling Approach. Math. Comput. Appl. 2021, 26, 25.

AMA Style

Gonzalez-Parra G, Martínez-Rodríguez D, Villanueva-Micó RJ. Impact of a New SARS-CoV-2 Variant on the Population: A Mathematical Modeling Approach. Mathematical and Computational Applications. 2021; 26(2):25.

Chicago/Turabian Style

Gonzalez-Parra, Gilberto; Martínez-Rodríguez, David; Villanueva-Micó, Rafael J. 2021. "Impact of a New SARS-CoV-2 Variant on the Population: A Mathematical Modeling Approach" Math. Comput. Appl. 26, no. 2: 25.

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