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Article

Illicit Drugs—Infections and Neonatal Anthropometric Characteristics

by
Leonard Năstase
1,2,*,
Silvia-Maria Stoicescu
1,2,
Nicolae Suciu
1,2,
Laurenţiu Camil Bohîlţea
1,2,*,
Eugenia Panaitescu
1 and
Adina-Brânduşa Baciu
3,4
1
Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania
2
“Alessandrescu-Rusescu” National Institute for Mother and Child Health, Bucharest, Romania
3
Institute of Anthropology, “Francisc I. Rainer" of the Romanian Academy, Bucharest, Romania
4
Faculty of Sociology and Social Work, University of Bucharest, 050663 Bucharest, Romania
*
Authors to whom correspondence should be addressed.
GERMS 2025, 15(2), 157-165; https://doi.org/10.18683/germs.2025.1465
Submission received: 16 April 2025 / Revised: 31 May 2025 / Accepted: 30 June 2025 / Published: 30 June 2025

Abstract

Introduction: The effects of drug addiction in pregnancy are associated with multiple maternal, fetal and neonatal risks in the short and long term. Methods: This was a retrospective descriptive study conducted in the National Institute for Maternal and Child Health "Alessandrescu-Rusescu" Bucharest, Romania - "Polizu" Hospital of Obstetrics and Gynecology (higher level maternity hospital), includes newborns from the last 22 years (2002–2024) from mothers who used illicit drugs before and during pregnancy. Results: The incidence of newborns born to mothers with drug addiction has steadily increased over the period studied, especially in the last 12 years. Neonatal morbidity was marked by: withdrawal syndrome (61.2% of cases), risk of congenital/perinatal infections through maternal infections (58.16%), prematurity (43.87%), birth weight ≤2500 g (55.10%), intrauterine growth restriction. Conclusions: Illicit drug use in pregnancy, associated with prematurity, intrauterine growth restriction, neonatal withdrawal syndrome, risk of congenital/perinatal infections through maternal infections, is an important risk factor for neonatal morbidity and mortality.
Keywords: drugs; pregnancy; intrauterine and neonatal morbidity drugs; pregnancy; intrauterine and neonatal morbidity

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MDPI and ACS Style

Năstase, L.; Stoicescu, S.-M.; Suciu, N.; Bohîlţea, L.C.; Panaitescu, E.; Baciu, A.-B. Illicit Drugs—Infections and Neonatal Anthropometric Characteristics. GERMS 2025, 15, 157-165. https://doi.org/10.18683/germs.2025.1465

AMA Style

Năstase L, Stoicescu S-M, Suciu N, Bohîlţea LC, Panaitescu E, Baciu A-B. Illicit Drugs—Infections and Neonatal Anthropometric Characteristics. GERMS. 2025; 15(2):157-165. https://doi.org/10.18683/germs.2025.1465

Chicago/Turabian Style

Năstase, Leonard, Silvia-Maria Stoicescu, Nicolae Suciu, Laurenţiu Camil Bohîlţea, Eugenia Panaitescu, and Adina-Brânduşa Baciu. 2025. "Illicit Drugs—Infections and Neonatal Anthropometric Characteristics" GERMS 15, no. 2: 157-165. https://doi.org/10.18683/germs.2025.1465

APA Style

Năstase, L., Stoicescu, S.-M., Suciu, N., Bohîlţea, L. C., Panaitescu, E., & Baciu, A.-B. (2025). Illicit Drugs—Infections and Neonatal Anthropometric Characteristics. GERMS, 15(2), 157-165. https://doi.org/10.18683/germs.2025.1465

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