Next Article in Journal
Minimally-Invasive Definitive Treatment of Recurrent Sialadenitis Due to Obstructive Sialolithiasis—A Case Report
Previous Article in Journal
Disseminated Bacillus Calmette-Guérin (BCG) Infection Presenting as Severe Respiratory Failure and Septic Shock
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
GERMS
Volume 13
Issue 3
10.18683/germs.2023.1396
germs-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
GERMS is published by MDPI from Volume 25 Issue 4 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with the former publisher Infection Science Forum S.R.L..
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Finding of Anaerococcus hydrogenalis in Blood Using Cell-Free DNA Technique in a Patient with Infective Endocarditis

by
Tulika Chatterjee
1,*,
Moni Roy
1,2,
Yeshaswini Panathur Sreenivasa Reddy
1 and
Sharjeel Ahmad
1
1
University of Illinois College of Medicine, Peoria, IL 61605, USA
2
OSF St. Francis Medical Center, Peoria, IL 61637, USA
*
Author to whom correspondence should be addressed.
GERMS 2023, 13(3), 282-287; https://doi.org/10.18683/germs.2023.1396
Submission received: 7 March 2023 / Revised: 16 August 2023 / Accepted: 31 August 2023 / Published: 30 September 2023
Versions Notes

Abstract

Introduction: The annual incidence of infective endocarditis (IE) is 3–9 cases per 100,000 in developed countries and most cases are due to staphylococci and streptococci. IE due to Gram-positive anaerobic cocci (GPAC) is very rare. Case report: We present a case of a 38-year-old female with Anaerococcus hydrogenalis bacteremia and infective endocarditis of the native mitral valve. She presented with fever, chills, and abdominal pain. A computed tomographic scan of the abdomen showed splenic abscesses. Blood cultures and broad-range PCR from the splenic abscess sample were negative. Transthoracic echocardiography showed a mobile filamentous structure on the atrial side of the anterior mitral leaflet which was suggestive for infective endocarditis. Karius test (cell-free microbial DNA testing) showed Gram-positive anaerobic cocci Anaerococcus hydrogenalis. She was successfully treated with antibiotics. Conclusions: In cases of infection with fastidious organisms like GPACs, the use of next-generation sequencing (NGS) can allow the correct identification of culprit pathogens and streamlined treatment.
Keywords: Gram-positive anaerobic cocci; Anaerococcus hydrogenalis; infective endocarditis; Gram-positive cocci; Anaerococcus species; cell-free microbial DNA testing; Karius test Gram-positive anaerobic cocci; Anaerococcus hydrogenalis; infective endocarditis; Gram-positive cocci; Anaerococcus species; cell-free microbial DNA testing; Karius test

Share and Cite

MDPI and ACS Style

Chatterjee, T.; Roy, M.; Reddy, Y.P.S.; Ahmad, S. Finding of Anaerococcus hydrogenalis in Blood Using Cell-Free DNA Technique in a Patient with Infective Endocarditis. GERMS 2023, 13, 282-287. https://doi.org/10.18683/germs.2023.1396

AMA Style

Chatterjee T, Roy M, Reddy YPS, Ahmad S. Finding of Anaerococcus hydrogenalis in Blood Using Cell-Free DNA Technique in a Patient with Infective Endocarditis. GERMS. 2023; 13(3):282-287. https://doi.org/10.18683/germs.2023.1396

Chicago/Turabian Style

Chatterjee, Tulika, Moni Roy, Yeshaswini Panathur Sreenivasa Reddy, and Sharjeel Ahmad. 2023. "Finding of Anaerococcus hydrogenalis in Blood Using Cell-Free DNA Technique in a Patient with Infective Endocarditis" GERMS 13, no. 3: 282-287. https://doi.org/10.18683/germs.2023.1396

APA Style

Chatterjee, T., Roy, M., Reddy, Y. P. S., & Ahmad, S. (2023). Finding of Anaerococcus hydrogenalis in Blood Using Cell-Free DNA Technique in a Patient with Infective Endocarditis. GERMS, 13(3), 282-287. https://doi.org/10.18683/germs.2023.1396

Article Metrics

Back to TopTop