Next Article in Journal
Recovery of Rare Earth Elements (REEs) Using Ionic Solvents
Next Article in Special Issue
PROMANCOA Modular Technology for the Valorization of Mango (Mangifera indica L.) and Cocoa (Theobroma cacao L.) Agricultural Biowastes
Previous Article in Journal
Towards Full Utilization of Biomass Resources: A Case Study on Industrial Hemp Residue and Spent Mushroom Substrate
Article

UPLC-QToF Nanospray MS and NMR Analysis of Ficus sycomorus Stem Bark and Its Effects on Rabbit

1
Department of Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, University of Sadat City, Menofia 32897, Egypt
2
Department of Physiology, Faculty of Veterinary Medicine, University of Sadat City, Menofia 32897, Egypt
3
Department of Parasitology, Faculty of Veterinary Medicine, University of Sadat City, Menofia 32897, Egypt
4
Department of Analytical Chemistry, Faculty of Pharmacy, University of Sadat City, Menofia 32897, Egypt
5
Division of Pharmacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, Box 574, SE-751 23 Uppsala, Sweden
6
Department of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt
7
Avian and Rabbit Diseases Department, Faculty of Veterinary Medicine, Sadat City University, Menofia 32897, Egypt
8
Research and Development Section, PerNaturam GmbH, 56290 Gödenroth, Germany
9
Department of Pathology, Faculty of Veterinary Medicine, University of Sadat City, Menofia 32897, Egypt
*
Authors to whom correspondence should be addressed.
Academic Editor: Ibrahim M. Abu-Reidah
Processes 2021, 9(7), 1201; https://doi.org/10.3390/pr9071201
Received: 26 June 2021 / Revised: 5 July 2021 / Accepted: 8 July 2021 / Published: 12 July 2021
In the present study, a phytochemical of Ficus sycomorus (Moraceae family) was screened, and the effect of this extract on rabbit performance indices, immunity, and carcass quality measures was determined. Ficus sycomorus samples were collected, air-dried, and extracted with 70% methanol to prepare a solution of 100 mg/mL concentration. The extract was subjected to high-resolution mass spectrometric measurements via ultra-high performance liquid chromatography-quadrupole time-of-flight-nanospray mass spectrometry (UPLC-QToF-MS) and 1H NMR analysis. Forty-eight male rabbits, one-month-old, belonging to the Blanc de Bouscat and New Zealand White breeds were selected and distributed equally in a 2 × 3 factorial trial. The rabbits within each breed received F. sycomorus extract at the dose of 0, 100, and 200 mg/kg for 60 days. Blood samples were collected and serum obtained for the detection of liver enzymes, serum lipids, and proteins. The results of UPLC-QToF-MS and molecular networking analysis revealed the presence of procyanidin B2, procyanidin A1, genistein, eriodyctiol, catechin, luteolin, biochanin A, and chlorogenic acid that might exhibit various pharmaceutical activities. However, the F. sycomorus extract reduced rabbit performance indices and carcass quality measures. In addition, this extract significantly depressed the low-density lipoprotein and triglycerides, which may indicate the antidyslipidemia effect of this extract on rabbits. View Full-Text
Keywords: Ficus sycomorus; UPLC-QToF nanospray MS; NMR analysis; antidyslipidemia effect; rabbits Ficus sycomorus; UPLC-QToF nanospray MS; NMR analysis; antidyslipidemia effect; rabbits
Show Figures

Figure 1

MDPI and ACS Style

Dawod, A.; Fathalla, S.I.; Elkhatam, A.; Osman, N.; Sheraiba, N.; Hammad, M.A.; El-Seedi, H.R.; Shehata, A.A.; Anis, A. UPLC-QToF Nanospray MS and NMR Analysis of Ficus sycomorus Stem Bark and Its Effects on Rabbit. Processes 2021, 9, 1201. https://doi.org/10.3390/pr9071201

AMA Style

Dawod A, Fathalla SI, Elkhatam A, Osman N, Sheraiba N, Hammad MA, El-Seedi HR, Shehata AA, Anis A. UPLC-QToF Nanospray MS and NMR Analysis of Ficus sycomorus Stem Bark and Its Effects on Rabbit. Processes. 2021; 9(7):1201. https://doi.org/10.3390/pr9071201

Chicago/Turabian Style

Dawod, Ahmed, Said I. Fathalla, Ahmed Elkhatam, Noha Osman, Nagwa Sheraiba, Mohamed A. Hammad, Hesham R. El-Seedi, Awad A. Shehata, and Anis Anis. 2021. "UPLC-QToF Nanospray MS and NMR Analysis of Ficus sycomorus Stem Bark and Its Effects on Rabbit" Processes 9, no. 7: 1201. https://doi.org/10.3390/pr9071201

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop