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Volume 13
Issue 9
10.3390/pr13092685
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This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Review

Marine Metabolites for the Sustainable and Renewable Production of Key Platform Chemicals

by
Maedeh Baharlooeian
1,
Menny M. Benjamin
2,
Shifali Choudhary
3,
Amin Hosseinian
4,
George S. Hanna
5 and
Mark T. Hamann
2,5,*
1
Department of Marine Biology, Faculty of Marine Science and Oceanography, Khorramshahr University of Marine Science and Technology, Khorramshahr 64199-34619, Iran
2
Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USA
3
Department of Biotechnology, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore 632014, India
4
Department of Chemistry, Faculty of Sciences, University of Hormozgan, Bandar Abbas 71961-93145, Iran
5
Department of Public Health Sciences, College of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
*
Author to whom correspondence should be addressed.
Processes 2025, 13(9), 2685; https://doi.org/10.3390/pr13092685 (registering DOI)
Submission received: 23 June 2025 / Revised: 22 July 2025 / Accepted: 21 August 2025 / Published: 23 August 2025
(This article belongs to the Section Pharmaceutical Processes)
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Abstract

Petrochemicals currently represent the predominant global source of energy and consumer products, including the starting materials used in the platform chemical, plastic polymer, and pharmaceutical industries. However, in recent years, the world’s approaches have shifted towards green chemistry and bio-based chemical production in an effort to reduce CO2 emissions and mitigate climate change. Over the past few decades, researchers have discovered that marine metabolites, primarily sourced from invertebrates, can be utilized to create sustainable and renewable chemicals. This review highlights the significance of advancing marine microorganism-based biotechnology and biochemistry in developing effective conversion systems to enhance the biological production of key platform chemicals, including those utilized as biomaterials and for energy. A background in marine metabolite biochemistry lays the groundwork for potential strategies to mitigate dependence on petroleum for consumer products. This is followed by a discussion of petroleum product replacement technologies, green chemistry alternatives, and CO2 mitigation efforts for the production of sustainable and renewable key platform chemicals.
Keywords: marine metabolites; marine drug production; platform chemicals; petroleum replacement; green energy; materials processing marine metabolites; marine drug production; platform chemicals; petroleum replacement; green energy; materials processing
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MDPI and ACS Style

Baharlooeian, M.; Benjamin, M.M.; Choudhary, S.; Hosseinian, A.; Hanna, G.S.; Hamann, M.T. Marine Metabolites for the Sustainable and Renewable Production of Key Platform Chemicals. Processes 2025, 13, 2685. https://doi.org/10.3390/pr13092685

AMA Style

Baharlooeian M, Benjamin MM, Choudhary S, Hosseinian A, Hanna GS, Hamann MT. Marine Metabolites for the Sustainable and Renewable Production of Key Platform Chemicals. Processes. 2025; 13(9):2685. https://doi.org/10.3390/pr13092685

Chicago/Turabian Style

Baharlooeian, Maedeh, Menny M. Benjamin, Shifali Choudhary, Amin Hosseinian, George S. Hanna, and Mark T. Hamann. 2025. "Marine Metabolites for the Sustainable and Renewable Production of Key Platform Chemicals" Processes 13, no. 9: 2685. https://doi.org/10.3390/pr13092685

APA Style

Baharlooeian, M., Benjamin, M. M., Choudhary, S., Hosseinian, A., Hanna, G. S., & Hamann, M. T. (2025). Marine Metabolites for the Sustainable and Renewable Production of Key Platform Chemicals. Processes, 13(9), 2685. https://doi.org/10.3390/pr13092685

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