Genotoxicity of Paragonimus heterotremus Infection in a Rat Model of Simultaneous Pulmonary and Hepatic Paragonimiasis
Abstract
:1. Introduction
2. Materials and Methods
2.1. Rat Infecting
2.2. Preparation of Single-Cell Suspensions
2.3. Alkaline Single-Cell Gel Electrophoresis (Comet) Assay
2.4. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Index | Control | Lung | Liver | |||
---|---|---|---|---|---|---|
Lung | Liver | Close | Remote | Close | Remote | |
GDI | 0.48 ± 0.034 | 0.18 ± 0.013 | 1.33 ± 0.093 | 0.82 ± 0.057 | 1.23 ± 0.0161 | 0.68 ± 0.048 |
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Chelomina, G.N.; Kukla, S.P.; Chelomin, V.P.; Doanh, P.N. Genotoxicity of Paragonimus heterotremus Infection in a Rat Model of Simultaneous Pulmonary and Hepatic Paragonimiasis. Biomedicines 2021, 9, 1180. https://doi.org/10.3390/biomedicines9091180
Chelomina GN, Kukla SP, Chelomin VP, Doanh PN. Genotoxicity of Paragonimus heterotremus Infection in a Rat Model of Simultaneous Pulmonary and Hepatic Paragonimiasis. Biomedicines. 2021; 9(9):1180. https://doi.org/10.3390/biomedicines9091180
Chicago/Turabian StyleChelomina, Galina N., Sergey P. Kukla, Viktor P. Chelomin, and Pham N. Doanh. 2021. "Genotoxicity of Paragonimus heterotremus Infection in a Rat Model of Simultaneous Pulmonary and Hepatic Paragonimiasis" Biomedicines 9, no. 9: 1180. https://doi.org/10.3390/biomedicines9091180