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Endocrine-Disrupting Chemicals and Insulin Resistance in Children

Department of Pediatrics, University of Chieti, I-66100 Chieti, Italy
Author to whom correspondence should be addressed.
Biomedicines 2020, 8(6), 137;
Received: 23 April 2020 / Revised: 24 May 2020 / Accepted: 25 May 2020 / Published: 28 May 2020
(This article belongs to the Section Therapeutic Strategies in Different Diseases)
The purpose of this article is to review the evidence linking background exposure to endocrine-disrupting chemicals (EDCs) with insulin resistance in children. Although evidence in children is scarce since very few prospective studies exist even in adults, evidence that EDCs might be involved in the development of insulin resistance and related diseases such as obesity and diabetes is accumulating. We reviewed the literature on both cross-sectional and prospective studies in humans and experimental studies. Epidemiological studies show a statistical link between exposure to pesticides, polychlorinated bisphenyls, bisphenol A, phthalates, aromatic polycyclic hydrocarbides, or dioxins and insulin resistance. View Full-Text
Keywords: endocrine-disrupting chemicals; insulin resistance endocrine-disrupting chemicals; insulin resistance
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Rotondo, E.; Chiarelli, F. Endocrine-Disrupting Chemicals and Insulin Resistance in Children. Biomedicines 2020, 8, 137.

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