Para-Anastomotic Pseudoaneurysms as a Long-Term Complication After Surgical Treatment of Peripheral Artery Disease: Clinical Characteristics and Surgical Treatment
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Population
2.2. Anastomotic Pseudoaneurysm Diagnostic Criteria
2.3. Treatment Methods
2.4. Term Definitions
2.5. Data Analyzed in the Study
2.6. Statistical Analysis
3. Results
3.1. Demographic and Descriptive Data of the Patients
3.2. Characteristics of Anastomotic Aneurysms
3.3. Perioperative Data and Short-Term Outcomes
3.4. Patients’ Long-Term Outcomes After Anastomotic Aneurysm Treatment
3.4.1. Graft Patency
3.4.2. Anastomotic Pseudoaneurysm Recurrence
3.4.3. Overall Survival
4. Discussion
Limitations of the Study
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable | n (%), Mean/Median (Range, SD/IQR) |
---|---|
Age (years) | 67.45 (54–83, SD: 6.89) |
Gender | |
Male | 41 (74.55%) |
Female | 14 (25.45%) |
Presence of comorbidities (yes) | 49 (89.09%) |
Arterial hypertension | 38 (69.09%) |
General atherosclerosis | 26 (47.27%) |
Coronary artery disease | 19 (34.55%) |
Diabetes mellitus | 15 (27.27%) |
History of myocardial infarction | 13 (23.64%) |
Dyslipidemia | 11 (20.00%) |
Heart failure | 7 (12.73%) |
COPD | 1 (1.82%) |
Dialysis dependence | 1 (1.82%) |
History of cigarette smoking (yes) | 30 (54.55%) |
Current cigarette smoking (yes) | 21 (38.18%) |
Clinical symptoms (yes) | 34 (61.82%) |
Lower-limb pain | 19 (34.55%) |
Intermittent claudication | 9 (16.36%) |
Ulcer | 4 (7.27%) |
Aneurysm rupture | 4 (7.27%) |
Acute limb ischemia | 3 (5.45%) |
Gangrene | 2 (3.64%) |
Limb swelling | 2 (3.64%) |
Variable | n (%), Mean/Median (Range, SD/IQR) |
---|---|
Primary anastomosis | |
Aortobifemoral bypass | 36 (65.46%) |
Femoropopliteal bypass | 11 (20.00%) |
Iliofemoral bypass | 5 (9.09%) |
Aortofemoral bypass | 3 (5.45%) |
Time after primary procedure to diagnosis of anastomotic aneurysm (years) | 8.78 (0.21–25.24, IQR: 8.70) |
Time after primary procedure to diagnosis of anastomotic pseudoaneurysm (time groups) | |
Less than 1 year | 2 (3.64%) |
1–5 years | 7 (12.73%) |
6–10 years | 27 (49.09%) |
More than 10 years | 19 (34.55%) |
Anastomotic pseudoaneurysm localization | |
Common femoral artery | 50 (90.91%) |
Popliteal artery | 3 (5.45%) |
Superficial femoral artery | 1 (1.82%) |
Deep femoral artery | 1 (1.82%) |
Pseudoaneurysm size (mm) | 38 (18–260, IQR: 24) |
Variable | n (%), Mean/Median (Range, SD/IQR) |
---|---|
Duration of procedure (minutes) | 150 (55–365, IQR: 60) |
Type of procedure | |
Aneurysmectomy with graft interposition | 46 (83.64%) |
Aneurysmectomy with extra-anatomical bypass | 6 (10.91%) |
EVAR | 3 (5.45%) |
Intraoperative blood loss | |
<400 mL | 52 (94.55%) |
>400 mL | 3 (5.45%) |
Transfusion of red blood cells | 2 (3.64%) |
Transfusion of fresh frozen plasma | 1 (1.82%) |
Graft material | |
Synthetic | 47 (85.45%) |
Patient’s vein | 4 (7.27%) |
Non-reversed saphenous vein | 3 (5.45%) |
In situ saphenous vein | 1 (1.82%) |
Duration of hospitalization (days) | 8 (4–100, IQR: 4) |
Duration of hospitalization after procedure (days) | 4 (2–90, IQR: 4) |
Postoperative complications (yes) * | 9 (16.36%) |
Acute limb ischemia | 3 (5.45%) |
Surgical site infection | 3 (5.45%) |
Myocardial infarction | 2 (3.64%) |
Hematoma | 2 (3.64%) |
Reoperations | 5 (11.11%) |
Variable | n (%), Mean/Median (Range, SD/IQR) |
---|---|
Follow-up time (months) | 16.5 (1–67, IQR: 33) |
Late complications * | 17 (30.91%) |
Acute limb ischemia | 4 (7.27%) |
Graft infection | 4 (7.27%) |
Anastomotic aneurysm recurrence | 4 (7.27%) |
Chronic limb ischemia | 2 (3.64%) |
Myocardial infarction | 2 (3.64%) |
Late reoperations | 10 (18.18%) |
Mortality | 6 (10.91%) |
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Łacna, J.; Serafin, M.; Łyko-Morawska, D.; Szostek, J.; Stańczyk, D.; Kania, I.; Mąka, M.; Kuczmik, W. Para-Anastomotic Pseudoaneurysms as a Long-Term Complication After Surgical Treatment of Peripheral Artery Disease: Clinical Characteristics and Surgical Treatment. Biomedicines 2024, 12, 2727. https://doi.org/10.3390/biomedicines12122727
Łacna J, Serafin M, Łyko-Morawska D, Szostek J, Stańczyk D, Kania I, Mąka M, Kuczmik W. Para-Anastomotic Pseudoaneurysms as a Long-Term Complication After Surgical Treatment of Peripheral Artery Disease: Clinical Characteristics and Surgical Treatment. Biomedicines. 2024; 12(12):2727. https://doi.org/10.3390/biomedicines12122727
Chicago/Turabian StyleŁacna, Julia, Michał Serafin, Dorota Łyko-Morawska, Julia Szostek, Dariusz Stańczyk, Iga Kania, Magdalena Mąka, and Waclaw Kuczmik. 2024. "Para-Anastomotic Pseudoaneurysms as a Long-Term Complication After Surgical Treatment of Peripheral Artery Disease: Clinical Characteristics and Surgical Treatment" Biomedicines 12, no. 12: 2727. https://doi.org/10.3390/biomedicines12122727
APA StyleŁacna, J., Serafin, M., Łyko-Morawska, D., Szostek, J., Stańczyk, D., Kania, I., Mąka, M., & Kuczmik, W. (2024). Para-Anastomotic Pseudoaneurysms as a Long-Term Complication After Surgical Treatment of Peripheral Artery Disease: Clinical Characteristics and Surgical Treatment. Biomedicines, 12(12), 2727. https://doi.org/10.3390/biomedicines12122727