Next Article in Journal
Observational Study on Antibody Response to COVID-19 Vaccines in PAtients with Gastro-Entero-PanCreatic Cancers and NeuroendocrIne NeoplAsms on Systemic TreatmEnts (VACCINATE)
Previous Article in Journal
iPSC-Derived Cardiomyocytes in Inherited Cardiac Arrhythmias: Pathomechanistic Discovery and Drug Development
Previous Article in Special Issue
Discordant Amyloid Status Diagnosis in Alzheimer’s Disease
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.

The Future of Precision Medicine in the Cure of Alzheimer’s Disease

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia
Department of Medical Elementology and Toxicology, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi 110062, India
Department of Pathology, Government Medical College, (GMC-Srinagar), Karan Nagar, Srinagar 190010, India
Department of Pharmacology and Toxicology, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia
Department of Molecular Pharmacology & Physiology, Bryd Alzheimer’s Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33620, USA
Department of Pharmacy, Abu Areish General Hospital, Abu Areish 45911, Saudi Arabia
Department of Emergency and Accident, Abu Areish General Hospital, Abu Areish 45911, Saudi Arabia
Division of Veterinary Biochemistry, Faculty of Veterinary Sciences and Animal Husbandry, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-K), Srinagar 190006, India
Novel Global Community Educational Foundation, Hebersham, NSW 2770, Australia
AFNP Med, Haidingergasse 29, 1030 Vienna, Austria
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Biomedicines 2023, 11(2), 335;
Received: 25 December 2022 / Revised: 18 January 2023 / Accepted: 18 January 2023 / Published: 25 January 2023
(This article belongs to the Special Issue Advanced Diagnostic and Treatment Methods in Alzheimer's Disease)


This decade has seen the beginning of ground-breaking conceptual shifts in the research of Alzheimer’s disease (AD), which acknowledges risk elements and the evolving wide spectrum of complicated underlying pathophysiology among the range of diverse neurodegenerative diseases. Significant improvements in diagnosis, treatments, and mitigation of AD are likely to result from the development and application of a comprehensive approach to precision medicine (PM), as is the case with several other diseases. This strategy will probably be based on the achievements made in more sophisticated research areas, including cancer. PM will require the direct integration of neurology, neuroscience, and psychiatry into a paradigm of the healthcare field that turns away from the isolated method. PM is biomarker-guided treatment at a systems level that incorporates findings of the thorough pathophysiology of neurodegenerative disorders as well as methodological developments. Comprehensive examination and categorization of interrelated and convergent disease processes, an explanation of the genomic and epigenetic drivers, a description of the spatial and temporal paths of natural history, biological markers, and risk markers, as well as aspects about the regulation, and the ethical, governmental, and sociocultural repercussions of findings at a subclinical level all require clarification and realistic execution. Advances toward a comprehensive systems-based approach to PM may finally usher in a new era of scientific and technical achievement that will help to end the complications of AD.
Keywords: precision medicine; Alzheimer’s disease; biomarkers; neuroimaging; artificial intelligence precision medicine; Alzheimer’s disease; biomarkers; neuroimaging; artificial intelligence

Share and Cite

MDPI and ACS Style

Arafah, A.; Khatoon, S.; Rasool, I.; Khan, A.; Rather, M.A.; Abujabal, K.A.; Faqih, Y.A.H.; Rashid, H.; Rashid, S.M.; Bilal Ahmad, S.; Alexiou, A.; U. Rehman, M. The Future of Precision Medicine in the Cure of Alzheimer’s Disease. Biomedicines 2023, 11, 335.

AMA Style

Arafah A, Khatoon S, Rasool I, Khan A, Rather MA, Abujabal KA, Faqih YAH, Rashid H, Rashid SM, Bilal Ahmad S, Alexiou A, U. Rehman M. The Future of Precision Medicine in the Cure of Alzheimer’s Disease. Biomedicines. 2023; 11(2):335.

Chicago/Turabian Style

Arafah, Azher, Saima Khatoon, Iyman Rasool, Andleeb Khan, Mashoque Ahmad Rather, Khaled Abdullah Abujabal, Yazid Abdullilah Hassan Faqih, Hina Rashid, Shahzada Mudasir Rashid, Sheikh Bilal Ahmad, Athanasios Alexiou, and Muneeb U. Rehman. 2023. "The Future of Precision Medicine in the Cure of Alzheimer’s Disease" Biomedicines 11, no. 2: 335.

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop