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by
  • Karolina Rowińska1,*,
  • Piotr Baszuk1 and
  • Emilia Rogoża-Janiszewska1
  • et al.

Reviewer 1: Vita Golubovskaya Reviewer 2: Eiji Kiyohara

Round 1

Reviewer 1 Report

The manuscript presents interesting data

on survival of melanoma patients and

content of Fe in serum. There are minor points ro address.

Fig.1. Please prepare better quality Figure.
Best is to use Prism Graph Pad software.

2. Please, include in Discussion review of

opposite data, discuss differences between  

groups, explain potential reasons of

different results.

3. Add some limitations of the study.

Author Response

We have responded to all the reviewer's comments in the attached PDF. Thank you for preparing the review for our publication.

Author Response File: Author Response.pdf

Reviewer 2 Report

The authors describe the association of serum iron with prognosis of melanoma. High risk group shows poor prognosis in melanoma patients. These data are informative for management of melanoma. I have the following suggestions.

1.      Ferroptosis of melanoma was described in other paper (ex. PMID: 35309911). You should discuss about ferroptosis in melanoma.

2.      There are too many examples of past papers in the discussion part. Association of melanoma with iron should be more discussed.

Author Response

We have responded to all the reviewer's comments in the attached PDF. Thank you for preparing the review for our publication.

Author Response File: Author Response.pdf