Analyzing the Electrochemical Interaction of the Angiogenesis Inhibitor Batimastat by Surface-Enhanced Raman Spectroscopy
Abstract
:1. Introduction
2. Materials and Methods
2.1. Theoretical Analysis
2.2. Raman and SERS Measurements
2.3. Electrode Preparation for SERS Study
3. Results and Discussion
3.1. Vibrational Characterization of Batimastat (BB-94)
3.2. SERS Detection of BB-94 on Silver Electrode
3.3. Analyzing Electrode-Potential Profiles of SERS Spectra of BB-94
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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νexp λ = 785 nm | νcalc B3LYP/6-31G | Assignment 1 |
---|---|---|
1660 vw | 1702 | ν(C=O)Ab, Amide I |
1643 vw | 1681 | ν(C=O)Aa, Amide I |
1606 w | 1596 | 8a; ν(CC)ring |
1585 vw | 1575 | 8b; ν(CC)ring |
1445 vw | 1468 | δ(CH3) |
1401 vs | 1407 | ν(CC)Thp |
1338 m | 1328 | ν(CC)Thp, δ(CH)Thp |
1298 w | 1277 | δ(NH), δ(CH2) |
1238 w | 1219 | ν(N-CO), δ(NH) |
1218 w | 1180 | ν(CX)ring, δ(NH) |
1158 w | 1146 | δ(CH2), δ(CH)ring |
1083 w | 1078 | δ(CH)Thp |
1032 w | 1017 | δ(CH)ring |
1002 m | 1001 | δ(CC)ring |
946 w | 942 | ν(CS)Thp |
845 w | 820 | δ(CSC)Thp |
825 vw | 807 | δ(CC)ring |
739 w | 738 | γ(CH)ring |
643 w | 689 | ν(S-CH2), γ(CH)Thp |
620 w | 610 | δ(CC)ring |
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Pięta, E.; Paluszkiewicz, C.; Kwiatek, W.M.; López-Ramírez, M.R. Analyzing the Electrochemical Interaction of the Angiogenesis Inhibitor Batimastat by Surface-Enhanced Raman Spectroscopy. Chemosensors 2023, 11, 128. https://doi.org/10.3390/chemosensors11020128
Pięta E, Paluszkiewicz C, Kwiatek WM, López-Ramírez MR. Analyzing the Electrochemical Interaction of the Angiogenesis Inhibitor Batimastat by Surface-Enhanced Raman Spectroscopy. Chemosensors. 2023; 11(2):128. https://doi.org/10.3390/chemosensors11020128
Chicago/Turabian StylePięta, Ewa, Czesława Paluszkiewicz, Wojciech M. Kwiatek, and María Rosa López-Ramírez. 2023. "Analyzing the Electrochemical Interaction of the Angiogenesis Inhibitor Batimastat by Surface-Enhanced Raman Spectroscopy" Chemosensors 11, no. 2: 128. https://doi.org/10.3390/chemosensors11020128