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Article

Novel Adiposity and Biochemical–Anthropometric Indices to Identify Cardiometabolic Risk and Metabolic Syndrome in Mexican Adults

1
Department of Medical Sciences, University of Guanajuato, León 37320, Mexico
2
Department of Pharmacy, University of Guanajuato, Guanajuato 36000, Mexico
*
Author to whom correspondence should be addressed.
These authors have contributed equally to this work.
Academic Editor: Edyta Mądry
Healthcare 2021, 9(11), 1561; https://doi.org/10.3390/healthcare9111561
Received: 8 October 2021 / Revised: 10 November 2021 / Accepted: 13 November 2021 / Published: 16 November 2021
Although several indices used in clinical practice identify cardiometabolic risk (CR) and metabolic syndrome (MetS), it is imperative to develop indices for specific populations. Therefore, we proposed and validated sex-specific indices to identify CR associated with visceral adipose tissue (VAT) accumulation or MetS in Mexican adults. Additionally, a cut-off value for the visceral fat area (VFA) to identify CR was proposed. Clinical, anthropometric, biochemical, and body composition variables were evaluated in 904 subjects (25–45 years old) (84.4% men). Multiple and logistic regressions were used to model the indices and ROC curve analysis to determine predictive performance. An additional cohort (n = 186) was used for indices validation, and Cohen’s kappa coefficient was employed for agreement analysis. The proposed sex-specific indices, called Mexican adiposity indices (MAIs) and biochemical–anthropometric indices (BAIs), were good predictors for CR and MetS. The kappa coefficients showed a moderate agreement level. The VFA cut-off value chosen to identify CR was 100.3 cm2 because it had the best combination of sensitivity (66.8%) and specificity (64.4%). MAIs and BAIs could be clinical tools to identify either CR associated to VAT accumulation or MetS, respectively. A VFA cut-off value of 100.3 cm2 could identify CR in Mexican men. View Full-Text
Keywords: visceral adipose tissue; cardiometabolic risk; metabolic syndrome; adiposity indices; insulin resistance indices visceral adipose tissue; cardiometabolic risk; metabolic syndrome; adiposity indices; insulin resistance indices
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MDPI and ACS Style

Rodríguez-Carrillo, P.L.; Aguirre-Tostado, P.I.; Macías-Cervantes, M.H.; Alegría-Torres, J.A.; Luevano-Contreras, C. Novel Adiposity and Biochemical–Anthropometric Indices to Identify Cardiometabolic Risk and Metabolic Syndrome in Mexican Adults. Healthcare 2021, 9, 1561. https://doi.org/10.3390/healthcare9111561

AMA Style

Rodríguez-Carrillo PL, Aguirre-Tostado PI, Macías-Cervantes MH, Alegría-Torres JA, Luevano-Contreras C. Novel Adiposity and Biochemical–Anthropometric Indices to Identify Cardiometabolic Risk and Metabolic Syndrome in Mexican Adults. Healthcare. 2021; 9(11):1561. https://doi.org/10.3390/healthcare9111561

Chicago/Turabian Style

Rodríguez-Carrillo, Patricia Lizett, Priscila Irene Aguirre-Tostado, Maciste H. Macías-Cervantes, Jorge Alejandro Alegría-Torres, and Claudia Luevano-Contreras. 2021. "Novel Adiposity and Biochemical–Anthropometric Indices to Identify Cardiometabolic Risk and Metabolic Syndrome in Mexican Adults" Healthcare 9, no. 11: 1561. https://doi.org/10.3390/healthcare9111561

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