A Proactive Health Behavior Framework for Cognitive Impairment in Chinese Older Adults: Based on a Four-Factor and Logistic Regression Analysis
Highlights
- Psychological–social support and information-behavior execution are major protective factors against screening positivity on the AD8 Dementia Screening Interview (AD8) among Chinese older adults; each one-standard-deviation increase reduces screening-positive risk by 39% and 53%, respectively;
- Age significantly increases cognitive impairment risk (21.7% per 5-year increment).
- Strengthening psychological support and optimizing health information access could be core strategies for dementia prevention;
- Integrating family and community resources with digital health technologies may enhance cognitive health equity.
Abstract
1. Introduction
2. Materials and Methods
2.1. Research Object
2.1.1. Inclusion Criteria
2.1.2. Exclusion Criteria
2.2. Research Instruments
2.2.1. General Behavioral Data
2.2.2. Analysis of Relevant Scales
2.3. Statistical Methods
2.4. Ethical Review
3. Results
3.1. Descriptive Analysis of Proactive Health Behaviors
3.2. Results of Factor Analysis of Proactive Health Behavior
3.3. Firth Penalized Logistic Regression Analysis of Proactive Health Behavior Factors
4. Discussion
4.1. Research Status and Significance
4.2. Proactive Health Behavior Intervention Theory
4.2.1. Four Factors and Their Theoretical Mechanisms
4.2.2. Interpretation of Non-Significant Findings
4.3. Risk Prevention and Control Strategies of Cognitive Impairment Based on Proactive Health Behavior Theory
4.4. Study Limitations
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Sachdev, P.; Andrews, G.; Hobbs, M.J.; Sunderland, M.; Anderson, T.M. Neurocognitive disorders: Cluster 1 of the proposed meta-structure for DSM-V and ICD-11. Psychol. Med. 2009, 39, 2001–2012. [Google Scholar] [CrossRef] [PubMed]
- Halloway, S.; Wagner, M.; Tangney, C.; Lange-Maia, B.S.; Bennett, D.A.; Arvanitakis, Z.; Schoeny, M.E. Profiles of lifestyle health behaviors and cognitive decline in older adults. Alzheimer’s Dement. 2024, 20, 472–482. [Google Scholar] [CrossRef] [PubMed]
- Reparaz-Escudero, I.; Izquierdo, M.; Bischoff-Ferrari, H.A.; Martínez-Lage, P.; de Asteasu, M.L.S. Effect of long-term physical exercise and multi-domain interventions on cognitive function and the risk of mild cognitive impairment and dementia in older adults: A systematic review with meta-analysis. Ageing Res. Rev. 2024, 100, 102463. [Google Scholar] [CrossRef] [PubMed]
- Galvin, J.E.; Roe, C.M.; Powlishta, K.K.; Coats, M.A.; Muich, S.J.; Grant, E.; Miller, J.P.; Storandt, M.; Morris, J.C. The AD8: A brief informant interview to detect dementia. Neurology 2005, 65, 559–564. [Google Scholar] [CrossRef] [PubMed]
- Galvin, J.E.; Roe, C.M.; Coats, M.A.; Morris, J.C. Patient’s rating of cognitive ability: Using the AD-8, a brief informant interview, as a self-rating tool to detect dementia. Arch. Neurol. 2007, 64, 725–730. [Google Scholar] [CrossRef] [PubMed]
- Li, T.; Wang, H.L.; Yang, Y.H.; Galvin, J.E.; Morris, J.C.; Yu, X. Preliminary study on the reliability and validity of the Chinese version of AD8. Chin. J. Intern. Med. 2012, 51, 777–780. (In Chinese) [Google Scholar]
- Yang, Y.H.; Galvin, J.E.; Morris, J.C.; Lai, C.-L.; Chou, M.-C.; Liu, C.-K. Application of AD8 questionnaire to screen very mild dementia in Taiwanese. Am. J. Alzheimer’s Dis. Other Dement. 2011, 26, 134–138. [Google Scholar] [CrossRef] [PubMed]
- Tayama, J.; Ogawa, S.; Takeoka, A.; Kobayashi, M.; Shirabe, S. Item response theory-based validation of a short form of the Feeding Behavior Scale for Japanese adults. Medicine 2017, 96, e8334. [Google Scholar] [CrossRef] [PubMed]
- Wang, F.; Wu, Y.; Sun, X.; Wang, D.; Ming, W.-K.; Sun, X.; Wu, Y. Reliability and validity of the Chinese version of a short form of the family health scale. BMC Prim. Care 2022, 23, 108. [Google Scholar] [CrossRef] [PubMed]
- Sun, X.N.; Chen, K.; Wu, Y.C.; Tang, J.; Wang, F.; Sun, X.; He, M.; Wu, Y. Development of a short version of health literacy: Based on classical test theory and item response theory. Chin. Gen. Pract. 2024, 27, 2931–2940. (In Chinese) [Google Scholar]
- Kroenke, K.; Spitzer, R.L.; Williams, J.B. The PHQ-9: Validity of a brief depression severity measure. J. Gen. Intern. Med. 2001, 16, 606–613. [Google Scholar] [CrossRef] [PubMed]
- Spitzer, R.L.; Kroenke, K.; Williams, J.B.W.; Löwe, B. A brief measure for assessing generalized anxiety disorder: The GAD-7. Arch. Intern. Med. 2006, 166, 1092–1097. [Google Scholar] [CrossRef] [PubMed]
- Long, S.; Benoist, C.; Weidner, W. World Alzheimer Report 2023: Reducing Dementia Risk: Never Too Early, Never Too Late; Alzheimer’s Disease International: London, UK, 2023. [Google Scholar]
- Health China Action Promotion Committee. Health China Action (2019–2030) [Policy document]. 2019. Available online: http://www.gov.cn/xinwen/2019-07/15/content_5409694.htm (accessed on 18 February 2025). (In Chinese)
- Flearys, A.; Joseph, P.; Pappagianopoulos, J.E. Adolescent health literacy and health behaviors: A systematic review. J. Adolesc. 2018, 62, 116–127. [Google Scholar] [CrossRef] [PubMed]
- Liu, C.; Wang, D.; Lu, C.; Jiang, J.; Wang, X.; Chen, H.; Ju, X.; Zhang, X. What is the meaning of health literacy? A systematic review and qualitative synthesis. Fam. Med. Community Health 2020, 8, e000351. [Google Scholar] [CrossRef] [PubMed]
- World Health Organization. Global Action Plan on Digital Health [Policy Document]. 2023. Available online: http://www.who.int/publications/i/item/9789240020924 (accessed on 19 February 2025).
- Visontay, R.; Rao, R.T.; Mewton, L. Alcohol use and dementia: New research directions. Curr. Opin. Psychiatry 2021, 34, 165–170. [Google Scholar] [CrossRef] [PubMed]
- Jones, A.; Ali, M.U.; Kenny, M.; Mayhew, A.; Mokashi, V.; He, H.; Lin, S.; Yavari, E.; Paik, K.; Subramanian, D.; et al. Potentially modifiable risk factors for dementia and mild cognitive impairment: An umbrella review and meta-analysis. Dement. Geriatr. Cogn. Disord. 2024, 53, 91–106. [Google Scholar] [CrossRef] [PubMed]
| Health Behavior | Assessment Scale | Purpose Description | Cronbach’s α |
|---|---|---|---|
| Dementia Screening Scale AD8 | Used for screening cognitive impairment; simple and rapid identification of at-risk populations [5,6,7] | 0.930 | |
| Rational Diet Behavior | Eating Behavior Scale (EBS-SF) | Evaluate the self-regulated dietary behavior of Participants [8] | 0.880 |
| Multidimensional Exercise Behavior | National Fitness Campaign NFC | Assess the frequency, intensity, duration, and type of physical activity participated in by Participants | 0.801 |
| Healthy Family Mutual Aid | Healthy Family Scale FHS-SF | Evaluate family health mutual aid and collaborative health management effectiveness [9] | 0.940 |
| Perceived Social Support | Perceived Social Support Scale (PSSS) | Assess the overall level of social support perceived by Participants | 0.952 |
| Health Maintenance Behavior | Health Literacy Scale HLS-SF12 | Evaluate medical resource utilization, disease control, and health promotion among Asian populations [10] | 0.921 |
| Psychological Behavior Non-Depression | Patient Health Questionnaire-9 (PHQ-9) | Assess depressive psychological behaviors of Participants including emotions, sleep, diet, and attention [11] | 0.922 |
| Psychological Behavior Non-Anxiety | Generalized Anxiety Disorder 7-Item Scale GAD-7 | Assess generalized anxiety psychological behaviors of Participants over the past two weeks [12] | 0.946 |
| Chronic Disease Management Behavior | Chronic Disease Self-Management Scale CDSMS | Evaluate the self-efficacy and adaptability of chronic disease patients in disease management | 0.945 |
| Variable | Options | Population Classification n (%) | χ2 | p | |
|---|---|---|---|---|---|
| Low-Risk Group | High-Risk Group | ||||
| Smoking Cessation Behavior | Not Quitted | 74 (12.8) | 84 (15.7) | 1.890 | 0.389 |
| Quitted | 119 (20.6) | 106 (19.8) | |||
| Never Smoked | 383 (66.5) | 344 (64.4) | |||
| Alcohol Restriction Behavior | No Restriction | 102 (17.7) | 82 (15.3) | 1.116 | 0.572 |
| Moderate Restriction | 87 (15.1) | 82 (15.3) | |||
| Complete Restriction | 387 (67.2) | 370 (69.3) | |||
| Salt Restriction Behavior | None | 69 (11.9) | 106 (19.8) | 18.063 | 0.001 * |
| One Type | 89 (15.4) | 96 (17.9) | |||
| Two Types | 218 (37.8) | 189 (35.4) | |||
| Three or More | 200 (34.7) | 143 (26.7) | |||
| Vaccination Behavior | Not Vaccinated | 113 (19.6) | 183 (34.3) | 29.674 | 0.080 |
| Vaccinated | 463 (80.4) | 351 (65.7) | |||
| Variable | Population Classification (M [Q1, Q3]) | Mann–Whitney U Statistic | p | |
|---|---|---|---|---|
| Low-Risk Group | High-Risk Group | |||
| Self-Regulated Diet Behavior | 21 [17, 25] | 21 [18, 24] | 145,577 | 0.122 |
| Multidimensional Exercise Behavior | 4 [3, 8] | 3 [2, 4.75] | 191,895 | 0.000 * |
| Family Mutual Assistance Behavior | 20 [17, 24] | 20 [18, 23] | 153,959 | 0.975 |
| Perceived Social Support Behavior | 61 [51, 72] | 48 [39.25, 57] | 242,268 | 0.000 * |
| Health Maintenance Behavior | 36 [32, 37] | 32 [28, 36] | 206,533 | 0.000 * |
| Non-Depressive Psychological Behavior | 25 [19, 27] | 22 [18, 25] | 193,064 | 0.000 * |
| Non-Anxious Psychological Behavior | 20 [15, 21] | 17 [14, 21] | 187,530 | 0.000 * |
| Smart Product Use Behavior | 60 [28.75, 83] | 56 [23, 80] | 164,741 | 0.040 * |
| Media Use Behavior | 12 [7, 15] | 8 [4, 13] | 191,602 | 0.000 * |
| Environmental Health Promotion Behavior | 79 [58, 98.5] | 79 [56.62, 99] | 155,107 | 0.804 |
| Chronic Disease Self-Management Behavior | 11 [6, 15] | 10 [6, 13] | 170,667 | 0.002 * |
| Variable | Rotated Factor Loading Coefficients | Communality | |||
|---|---|---|---|---|---|
| Factor 1 | Factor 2 | Factor 3 | Factor 4 | ||
| Smoking Cessation Behavior | 0.027 | −0.015 | 0.019 | 0.821 | 0.676 |
| Alcohol Restriction Behavior | −0.04 | −0.108 | 0.022 | 0.818 | 0.684 |
| Salt Restriction Behavior | 0.126 | 0.259 | 0.314 | 0.278 | 0.258 |
| Self-Regulated Diet Behavior | 0.576 | −0.206 | 0.008 | 0.108 | 0.386 |
| Multidimensional Exercise Behavior | −0.194 | 0.698 | 0.083 | −0.065 | 0.535 |
| Family Mutual Assistance Behavior | 0.640 | 0.149 | 0.070 | 0.099 | 0.446 |
| Perceived Social Support Behavior | 0.658 | 0.339 | 0.174 | 0.083 | 0.586 |
| Health Maintenance Behavior | 0.404 | 0.586 | 0.252 | 0.043 | 0.572 |
| Non-Depressive Psychological Behavior | 0.830 | −0.103 | 0.025 | −0.105 | 0.711 |
| Non-Anxious Psychological Behavior | 0.811 | −0.059 | −0.023 | −0.122 | 0.677 |
| Smart Home Device Use Behavior | −0.032 | 0.014 | 0.814 | −0.121 | 0.679 |
| Media Use Behavior | −0.031 | 0.779 | −0.036 | −0.047 | 0.611 |
| Environmental Health Promotion Behavior | 0.210 | 0.041 | 0.728 | 0.166 | 0.604 |
| Vaccination Behavior | 0.072 | 0.519 | 0.013 | −0.009 | 0.275 |
| Chronic Disease Self-Management Behavior | −0.302 | 0.419 | 0.383 | 0.002 | 0.413 |
| Variable | Variance Explained (%) | Cumulative Variance Explained (%) | Weight (%) |
|---|---|---|---|
| Factor 1 | 18.36 | 18.36 | 31.42 |
| Factor 2 | 16.39 | 34.75 | 28.04 |
| Factor 3 | 12.27 | 47.02 | 21 |
| Factor 4 | 11.43 | 58.45 | 19.55 |
| Variable | β | SE | Wald χ2 | p | OR | OR (95% CI) | Standardized OR (per1SD) | |
|---|---|---|---|---|---|---|---|---|
| Lower | Upper | (95% CI) | ||||||
| Factor 1 | −2.628 | 0.368 | 50.126 | 0.000 | 0.072 | 0.035 | 0.148 | 0.612 (0.381–0.984) |
| Factor 2 | −4.898 | 0.538 | 83.742 | 0.000 | 0.008 | 0.003 | 0.021 | 0.466 (0.272–0.797) |
| Factor 3 | −0.875 | 0.259 | 11.432 | 0.001 | 0.417 | 0.250 | 0.691 | 0.789 (0.576–1.080) |
| Factor 4 | −0.344 | 0.188 | 3.328 | 0.068 | 0.709 | 0.490 | 1.026 | 0.889 (0.663–1.191) |
| Age | 0.196 | 0.061 | 10.216 | 0.001 | 1.217 | 1.079 | 1.372 | - |
| Educational Attainment | −0.075 | 0.075 | 1.006 | 0.316 | 0.928 | 0.801 | 1.074 | - |
| Constant | 3.988 | 0.504 | 62.153 | 0.000 | 53.943 | 20.304 | 146.959 | - |
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Wang, S.; Liang, H. A Proactive Health Behavior Framework for Cognitive Impairment in Chinese Older Adults: Based on a Four-Factor and Logistic Regression Analysis. Healthcare 2026, 14, 164. https://doi.org/10.3390/healthcare14020164
Wang S, Liang H. A Proactive Health Behavior Framework for Cognitive Impairment in Chinese Older Adults: Based on a Four-Factor and Logistic Regression Analysis. Healthcare. 2026; 14(2):164. https://doi.org/10.3390/healthcare14020164
Chicago/Turabian StyleWang, Shengjiang, and Hailun Liang. 2026. "A Proactive Health Behavior Framework for Cognitive Impairment in Chinese Older Adults: Based on a Four-Factor and Logistic Regression Analysis" Healthcare 14, no. 2: 164. https://doi.org/10.3390/healthcare14020164
APA StyleWang, S., & Liang, H. (2026). A Proactive Health Behavior Framework for Cognitive Impairment in Chinese Older Adults: Based on a Four-Factor and Logistic Regression Analysis. Healthcare, 14(2), 164. https://doi.org/10.3390/healthcare14020164

