Next Article in Journal
Multilevel Modelling of Individual, Community and Regional Level Factors Associated with Insecticide-Treated Net Usage among Pregnant Women in Ethiopia
Previous Article in Journal
Food Intake Changes and Their Impact on Quality of Life in Spanish Citizens with and without COVID-19 during Lockdown
 
 
Article

Salivary Biomarker Profiles and Chronic Fatigue among Nurses Working Rotation Shifts: An Exploratory Pilot Study

1
Graduate School of Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
2
Faculty of Health Sciences, Hokkaido University, Sapporo 060-0812, Japan
3
Research Fellow of Japan Society for the Promotion of Science, Tokyo 102-0083, Japan
4
NEC Solution Innovators, Ltd., Tokyo 136-8627, Japan
5
Biostatics Division, Clinical Research and Medical Innovation Center, Hokkaido University Hospital, Sapporo 060-8648, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Susan Ka Yee Chow
Healthcare 2022, 10(8), 1416; https://doi.org/10.3390/healthcare10081416
Received: 10 July 2022 / Revised: 25 July 2022 / Accepted: 26 July 2022 / Published: 28 July 2022
(This article belongs to the Section Nursing)
Although nurses’ fatigue affects their well-being and patient safety, no effective objective measurements exist. We explored the profiles of salivary biomarkers associated with nurses’ chronic fatigue across several shifts. This longitudinal study involved 45 shiftwork nurses and collected their saliva samples before two night and two day shifts for a month. Chronic fatigue was measured using the Cumulative Fatigue Symptom Index before the first night shift. Biomarker profiles were analyzed using hierarchical cluster analysis, and chronic fatigue levels were compared between the profiles. Cortisol profiles were classified into high- and low-level groups across two day shifts; the low-level group presented significantly higher irritability and unwillingness to work. Secretory immunoglobulin A (s-IgA) profiles across the four shifts were classified into high- and low-level groups; the high-level group had significantly higher depressive feelings, decreased vitality, irritability, and unwillingness to work. Cortisol (two day shifts) and s-IgA (four shifts) profiles were combined, and (i) cortisol low-level and s-IgA high-level and (ii) cortisol high-level and s-IgA low-level groups were identified. The former group had significantly higher chronic fatigue sign and irritability than the latter group. The profiles of salivary cortisol and s-IgA across several shifts were associated with nurses’ chronic fatigue. View Full-Text
Keywords: nurses; fatigue; saliva; biomarkers; shift work schedule nurses; fatigue; saliva; biomarkers; shift work schedule
Show Figures

Figure 1

MDPI and ACS Style

Yamaguchi, S.; Watanabe, K.; Sugimura, N.; Shishido, I.; Konya, I.; Fujita, T.; Yoshimitsu, Y.; Kato, S.; Ito, Y.M.; Yano, R. Salivary Biomarker Profiles and Chronic Fatigue among Nurses Working Rotation Shifts: An Exploratory Pilot Study. Healthcare 2022, 10, 1416. https://doi.org/10.3390/healthcare10081416

AMA Style

Yamaguchi S, Watanabe K, Sugimura N, Shishido I, Konya I, Fujita T, Yoshimitsu Y, Kato S, Ito YM, Yano R. Salivary Biomarker Profiles and Chronic Fatigue among Nurses Working Rotation Shifts: An Exploratory Pilot Study. Healthcare. 2022; 10(8):1416. https://doi.org/10.3390/healthcare10081416

Chicago/Turabian Style

Yamaguchi, Shinya, Kazuhiro Watanabe, Naotaka Sugimura, Inaho Shishido, Issei Konya, Tomoko Fujita, Yuichi Yoshimitsu, Shintaro Kato, Yoichi M. Ito, and Rika Yano. 2022. "Salivary Biomarker Profiles and Chronic Fatigue among Nurses Working Rotation Shifts: An Exploratory Pilot Study" Healthcare 10, no. 8: 1416. https://doi.org/10.3390/healthcare10081416

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop