Safety of Chuna Manipulation Therapy in 289,953 Patients with Musculoskeletal Disorders: A Retrospective Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Population and Data Collection
2.2. Nursing Situation Reports and Routine Vigilance by Medical and Nursing Staff
2.3. Screening for AEs
2.4. Analysis of AEs
2.5. Patient and Public Involvement
2.6. Statistical Analysis
3. Results
3.1. Baseline Characteristics
3.2. Inter-Rater Agreement and Reliability Analysis
3.3. Types and Frequency of AEs
3.3.1. Worsening of Musculoskeletal Pain
3.3.2. Rib Fractures
3.3.3. Falls during Treatment
3.3.4. Vertigo, Chest Pain, and Unpleasant Sensation
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Characteristics | Total | Inpatient * | Outpatient |
---|---|---|---|
Patients, n | 289,953 | 47,965 | 241,988 |
CMT sessions, n | 2,682,258 | 807,103 | 1,875,155 |
Demographics | |||
Sex | |||
Female | 145,955 (50.3) | 24,531 (51.1) | 121,424 (50.2) |
Male | 143,998 (49.7) | 23,434 (48.9) | 120,564 (49.8) |
Age, years | |||
Mean ± SD | 40.6 ± 13.8 | 42.3 ± 14.1 | 40.22 ± 13.74 |
0–9 | 825 (0.3) | 70 (0.1) | 755 (0.3) |
10–19 | 8829 (3.0) | 885 (1.8) | 7944 (3.3) |
20–29 | 55,624 (19.2) | 8968 (18.7) | 46,656 (19.3) |
30–39 | 91,350 (31.5) | 13,275 (27.7) | 78,075 (32.3) |
40–49 | 56,908 (19.6) | 9389 (19.6) | 47,519 (19.6) |
50–59 | 45,164 (15.6) | 9047 (18.9) | 36,117 (14.9) |
60–69 | 22,790 (7.9) | 4760 (9.9) | 18,030 (7.5) |
70–79 | 7455 (2.6) | 1342 (2.8) | 6113 (2.5) |
≥80 | 1008 (0.3) | 229 (0.5) | 779 (0.3) |
District | |||
Seoul | 157,686 (54.4) | 14,271 (29.8) | 143,415 (59.3) |
Gyeonggi-do Province | 68,696 (23.7) | 10,658 (22.2) | 58,038 (24.0) |
Chungcheong-do Province | 41,722 (14.4) | 13,759 (28.7) | 27,963 (11.6) |
Gyeongsang-do Province | 11,585 (4.0) | 6486 (13.5) | 5099 (2.1) |
Jeolla-do Province | 10,264 (3.5) | 2791 (5.8) | 7473 (3.1) |
Treatment | |||
Admissions, n | - | 1.1 ± 0.5 | - |
Duration of admission, days | - | 15.0 ± 19.5 | - |
Outpatient visits | 7.4 ± 11.4 | 5.3 ± 11.7 † | 7.8 ± 11.3 |
CMT sessions per patient, n | 9.3 ± 13.5 | 16.8 ± 19.6 | 7.8 ± 11.3 |
Total (n = 2,184,722) | n (%) | |
---|---|---|
S134 | Sprain and strain of cervical spine | 415,270 (19.0) |
S335 | Sprain and strain of lumbar spine | 393,292 (18.0) |
M511 | Lumbar and other intervertebral disc disorder with radiculopathy | 260,068 (11.9) |
M519 | Intervertebral disc disorder, unspecified | 137,949 (6.3) |
M518 | Other specified intervertebral disc disorder | 112,307 (5.1) |
M545 | Low back pain | 108,010 (4.9) |
M501 | Cervical disc disorder with radiculopathy | 80,600 (3.7) |
M542 | Cervicalgia | 72,236 (3.3) |
M480 | Spinal stenosis | 68,988 (3.2) |
M509 | Cervical disc disorder, unspecified | 53,349 (2.4) |
Inpatient (n = 53,862) † | ||
S134 | Sprain and strain of cervical spine | 14,468 (26.9) |
S335 | Sprain and strain of lumbar spine | 12,446 (23.1) |
M511 | Lumbar and other intervertebral disc disorder with radiculopathy | 7834 (14.5) |
M501 | Cervical disc disorder with radiculopathy | 2870 (5.3) |
M518 | Other specified intervertebral disc disorder | 2281 (4.2) |
M480 | Spinal stenosis | 1663 (3.1) |
S836 | Sprain and strain of other and unspecified part of knee | 1293 (2.4) |
M545 | Low back pain | 1169 (2.2) |
M519 | Intervertebral disc disorder, unspecified | 746 (1.4) |
M255 | Joint pain | 589 (1.1) |
Outpatient (n = 2,130,860) ‡ | ||
S134 | Sprain and strain of cervical spine | 400,802 (18.8) |
S335 | Sprain and strain of lumbar spine | 380,846 (17.9) |
M511 | Lumbar and other intervertebral disc disorder with radiculopathy | 252,234 (11.8) |
M519 | Intervertebral disc disorder, unspecified | 137,203 (6.4) |
M518 | Other specified intervertebral disc disorder | 110,026 (5.2) |
M545 | Low back pain | 106,841 (5.0) |
M501 | Cervical disc disorder with radiculopathy | 77,730 (3.6) |
M542 | Cervicalgia | 71,788 (3.4) |
M480 | Spinal stenosis | 67,325 (3.2) |
M509 | Cervical disc disorder, unspecified | 52,968 (2.5) |
Case | Total | Severity § | |||||
---|---|---|---|---|---|---|---|
n | Incidence 1 * (95% CI) | Incidence 2 † (95% CI) | Frequency | Mild | Moderate | Severe | |
Classification ‡ | |||||||
Increased musculoskeletal pain or discomfort | 29 | 0.09 (0.06–0.12) | 1.08 (0.73–1.52) | Very rare | 9 | 19 | 1 |
Rib fracture | 11 | 0.03 (0.02–0.06) | 0.41 (0.21–0.70) | Very rare | 0 | 11 | 0 |
Falls | 6 | 0.02 (0.01–0.04) | 0.22 (0.09–0.45) | Very rare | 6 | 0 | 0 |
Dizziness | 1 | 0.003 (0.000–0.013) | 0.04 (0.00–0.16) | Very rare | 0 | 1 | 0 |
Chest pain without rib fracture | 2 | 0.01 (0.00–0.02) | 0.07 (0.01–0.23) | Very rare | 1 | 1 | 0 |
Mild discomfort | 1 | 0.003 (0.000–0.013) | 0.04 (0.00–0.16) | Very rare | 1 | 0 | 0 |
Total | 50 | 0.15 (0.11–0.19) | 1.86 (1.39–2.43) | Very rare | 17 | 32 | 1 |
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Kim, S.; Kim, G.-B.; Kim, H.-j.; Park, J.; Lee, J.-W.; Jeong, W.-j.; Kim, H.-G.; Kim, M.-Y.; Park, K.-S.; Lee, J.; et al. Safety of Chuna Manipulation Therapy in 289,953 Patients with Musculoskeletal Disorders: A Retrospective Study. Healthcare 2022, 10, 294. https://doi.org/10.3390/healthcare10020294
Kim S, Kim G-B, Kim H-j, Park J, Lee J-W, Jeong W-j, Kim H-G, Kim M-Y, Park K-S, Lee J, et al. Safety of Chuna Manipulation Therapy in 289,953 Patients with Musculoskeletal Disorders: A Retrospective Study. Healthcare. 2022; 10(2):294. https://doi.org/10.3390/healthcare10020294
Chicago/Turabian StyleKim, Suna, Gook-Beom Kim, Hyo-jun Kim, Joon Park, Ji-Won Lee, Wu-jin Jeong, Hye-Gyeong Kim, Min-Young Kim, Kyoung-Sun Park, Jinho Lee, and et al. 2022. "Safety of Chuna Manipulation Therapy in 289,953 Patients with Musculoskeletal Disorders: A Retrospective Study" Healthcare 10, no. 2: 294. https://doi.org/10.3390/healthcare10020294