High Doses of Essential Oil of Croton Zehntneri Induces Renal Tubular Damage
Abstract
:1. Introduction
2. Results
2.1. EOCZ Treatment Induces Changes in Renal Function Parameters
2.2. Urinary Protein Excretion Is Modulated by EOCZ Treatment
2.3. EOCZ Treatment Promotes Tubulointerstitial Injury
3. Discussion
4. Materials and Methods
4.1. Plant Material
4.2. Extraction and Chromatographic Analysis of EOCZ
4.3. Animals and Experimental Protocol
4.4. Renal Function Analysis
4.5. Histologic and Immunohistochemical Analyses
4.6. Statistical Analysis
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Silva, K.F.; Peruchetti, D.B.; Sirtoli, G.M.; Takiya, C.M.; Pinheiro, A.A.S.; Leal-Cardoso, J.H.; Caruso-Neves, C. High Doses of Essential Oil of Croton Zehntneri Induces Renal Tubular Damage. Plants 2021, 10, 1400. https://doi.org/10.3390/plants10071400
Silva KF, Peruchetti DB, Sirtoli GM, Takiya CM, Pinheiro AAS, Leal-Cardoso JH, Caruso-Neves C. High Doses of Essential Oil of Croton Zehntneri Induces Renal Tubular Damage. Plants. 2021; 10(7):1400. https://doi.org/10.3390/plants10071400
Chicago/Turabian StyleSilva, Katarine F., Diogo B. Peruchetti, Gabriela M. Sirtoli, Christina M. Takiya, Ana Acacia S. Pinheiro, José Henrique Leal-Cardoso, and Celso Caruso-Neves. 2021. "High Doses of Essential Oil of Croton Zehntneri Induces Renal Tubular Damage" Plants 10, no. 7: 1400. https://doi.org/10.3390/plants10071400