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Biomolecules 2018, 8(3), 80; https://doi.org/10.3390/biom8030080

Research Progress on the Relationship between Atherosclerosis and Inflammation

Laboratory Animal Center, Xuzhou Medical University, Xuzhou 221004, Jiangsu, China
These authors contributed equally to the work.
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Author to whom correspondence should be addressed.
Received: 14 June 2018 / Revised: 3 August 2018 / Accepted: 17 August 2018 / Published: 23 August 2018
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Abstract

Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture, vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute cardiovascular disease. Atherosclerosis-related inflammation is mediated by proinflammatory cytokines, inflammatory signaling pathways, bioactive lipids, and adhesion molecules. This review discusses the effects of inflammation and the systemic inflammatory signaling pathway on atherosclerosis, the role of related signaling pathways in inflammation, the formation of atherosclerosis plaques, and the prospects of treating atherosclerosis by inhibiting inflammation. View Full-Text
Keywords: atherosclerosis; inflammation; anti-inflammatory therapy atherosclerosis; inflammation; anti-inflammatory therapy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Zhu, Y.; Xian, X.; Wang, Z.; Bi, Y.; Chen, Q.; Han, X.; Tang, D.; Chen, R. Research Progress on the Relationship between Atherosclerosis and Inflammation. Biomolecules 2018, 8, 80.

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