Vitamin D and Autoimmune Rheumatic Diseases
Abstract
:1. Introduction
2. Vitamin D and Immunity
2.1. Vitamin D and Innate Immunity
2.2. Vitamin D and Dendritic Cells
2.3. Vitamin D and Adaptive Immune System
3. Vitamin D and Autoimmunity
4. Rheumatoid Arthritis and Vitamin D
5. Systemic Lupus Erythematosus and Vitamin D
6. Ankylosing Spondylitis and Vitamin D
7. Psoriatic Arthritis and Vitamin D
8. Sjogren’s Syndrome and Vitamin D
9. Systemic Sclerosis and Vitamin D
10. Inflammatory Myopathies and Vitamin D
11. Vitamin D Supplementation
12. Vitamin D Deficiency in Autoimmune Rheumatic Diseases
13. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Authors (Date) | Type of Study | Study Population | Results |
---|---|---|---|
Andjelkovic et al. (1999) [218] | Open label | RA = 19 | Improvement of clinical indices |
Gopinath and Danda (2011) [219] | Open label | RA = 121 | Improved pain relief |
Salesi et al. (2012) [220] | Double-blind | RA = 117 | Improved DAS28 |
Dheghan et al. (2014) [221] | RCT | RA = 80 | No improvement in relapse rate |
Hansen et al. (2014) [222] | RCT | RA = 22 | Improved bone formation |
Buondonno et al. (2017) [86] | RCT | RA = 70 | Reduced inflammatory cytokines |
Chandrashekara and Patted (2017) [223] | Open label | RA = 73 | Improved DAS28, CRP |
Mukherjee et al. (2019) [224] | Open label | RA = 25 | Improved pain |
Kwon et al. (2020) [225] | Open label | RA with osteoporosis = 187 | Improved bone mineral density |
Authors (Date) | Type of Study | Study Population | Results |
---|---|---|---|
Andreoli et al. (2015) [159] | Randomized prospective study | SLE = 34 female | No significant effect on clinical outcomes |
Aranow et al. (2015) [160] | Double-blind placebo controlled | SLE = 54 | No significant effects |
Karimzadeh et al. (2017) [161] | Double-blind placebo controlled | SLE = 90 | No significant effects |
Marinho et al. (2017) [162] | Prospective cross-sectional study | SLE = 24 | Decreased SLEDAI, immunologic effects |
Al-Kushi et al. (2018) [163] | RCT | SLE = 81 | Improved osteopenia osteoporosis |
Magro et al. (2021) [164] | Open label | SLE = 31 | Improved disease activity, fatique |
Kavadichanda et al. (2023) [165] | Cross sectional study | SLE = 702 | No significant effects |
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Athanassiou, L.; Kostoglou-Athanassiou, I.; Koutsilieris, M.; Shoenfeld, Y. Vitamin D and Autoimmune Rheumatic Diseases. Biomolecules 2023, 13, 709. https://doi.org/10.3390/biom13040709
Athanassiou L, Kostoglou-Athanassiou I, Koutsilieris M, Shoenfeld Y. Vitamin D and Autoimmune Rheumatic Diseases. Biomolecules. 2023; 13(4):709. https://doi.org/10.3390/biom13040709
Chicago/Turabian StyleAthanassiou, Lambros, Ifigenia Kostoglou-Athanassiou, Michael Koutsilieris, and Yehuda Shoenfeld. 2023. "Vitamin D and Autoimmune Rheumatic Diseases" Biomolecules 13, no. 4: 709. https://doi.org/10.3390/biom13040709
APA StyleAthanassiou, L., Kostoglou-Athanassiou, I., Koutsilieris, M., & Shoenfeld, Y. (2023). Vitamin D and Autoimmune Rheumatic Diseases. Biomolecules, 13(4), 709. https://doi.org/10.3390/biom13040709