A Standard Protocol for the Calibration of Capillary Electrophoresis (CE) Equipment

Bodo LACHMANN; Hannelore KOPELENT-FRANK; Christian R. NOE

doi:10.3797/scipharm.1109-23

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Article

6 October 2011

A Standard Protocol for the Calibration of Capillary Electrophoresis (CE) Equipment

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Department of Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria

Author to whom correspondence should be addressed.

Sci. Pharm.2011, 79(4), 877-884;https://doi.org/10.3797/scipharm.1109-23

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Abstract

Calibration of complex analytical systems is always a difficult task. Nevertheless, a suitable approach has to be designed before the systems can be introduced into routine analysis. In literature, many methods have been described for the purpose of calibrating such systems, but only a few of them deal with capillary elctrophoresis. Here, we want to demonstrate a general approach to how the calibration of this type of analytical instrument becomes feasible.

Keywords:

Capillary electrophoresis; Calibration of analytical instruments; GLP; ICH

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