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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Articles in this Issue were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Sci. Pharm. 2010, 78(3), 718; (registering DOI)

A Coupled Kinetic-Dynamic Model Characterising Cell Cycle Response to an Anti-Cancer Agent

School of Engineering, University of Warwick, Coventry, United Kingdom
University of Wales College of Medicine, Cardiff University, Cardiff, United Kingdom
Author to whom correspondence should be addressed.
Received: 12 July 2010 / Accepted: 12 July 2010 / Published: 12 July 2010
PDF [130 KB, uploaded 11 October 2016]


Topotecan (TPT) is a semi-synthetic derivative of the natural extract camptothecin, which has been found to act as an inhibitor of the DNA enzyme topoisomerase I in a specific and reversible fashion. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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ATARI, M.I.; CHAPPELL, M.J.; ERRINGTON, R.J.; SMITH, P.J.; EVANS, N.D. A Coupled Kinetic-Dynamic Model Characterising Cell Cycle Response to an Anti-Cancer Agent. Sci. Pharm. 2010, 78, 718.

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