A 3D model of the epithelial airway barrier to study uptake, cell responses and intracellular distribution of nanoparticles

B. ROTHEN-RUTISHAUSER; C. BRANDENBERGER; A. LEHMANN; P. GEHR

doi:10.3797/scipharm.cespt.8.L08

Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).

Conference Report

12 July 2010

A 3D model of the epithelial airway barrier to study uptake, cell responses and intracellular distribution of nanoparticles

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Institute of Anatomy, University of Bern, Bern, Switzerland

Author to whom correspondence should be addressed.

Sci. Pharm.2010, 78(3), 548;https://doi.org/10.3797/scipharm.cespt.8.L08

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Abstract

Understanding the intracellular localisation of biomedical nanoparticles (NPs), such as their co-localisation within cellular organells, e. g. endosomes, lysosomes, mitochondria or nuclei, or, alternatively free in the cytosol, can provide essential information in regard to the potential toxicity of NPs. [...]

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