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Volume 75
Issue 4
10.3797/scipharm.2007.75.179
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Article

Antioxidant Active Principles Isolated from Psidium guajava Grown in Thailand

by
Suganya Tachakittirungrod
1,
Fumio Ikegami
2 and
Siriporn Okonogi
1,*
1
Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200, Thailand
2
Center for Environment, Health and Field Sciences, Chiba University, Japan
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2007, 75(4), 179-193; https://doi.org/10.3797/scipharm.2007.75.179
Submission received: 15 September 2007 / Accepted: 10 November 2007 / Published: 31 December 2007
Versions Notes

Abstract

Antioxidant active compounds were isolated from methanol crude extracts of the leaves of Guava (Psidium guajava L.) grown in Thailand. The isolated compounds were screened for their in vitro antioxidant activity by a DPPH free radical scavenging assay. Results indicate that three isolated compounds contribute importantly to the antioxidant activity of guava leaves, providing a scientific basis for the use of this plant in traditional medicine. Their structures were determined on the basis of spectroscopic and chemical methods. The most active compound was found to be quercetin along with two flavonoid compounds, quercetin-3-O-glucopyranoside and morin. The isolated quercetin, quercetin-3-O-glucopyranoside and morin showed significant scavenging activity with IC50 of 1.20±0.02, 3.58±0.05 and 5.41±0.20 µg/ml, respectively.
Keywords: Guava; Psidium guajava; Flavonoid; Antioxidant activity Guava; Psidium guajava; Flavonoid; Antioxidant activity

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MDPI and ACS Style

Tachakittirungrod, S.; Ikegami, F.; Okonogi, S. Antioxidant Active Principles Isolated from Psidium guajava Grown in Thailand. Sci. Pharm. 2007, 75, 179-193. https://doi.org/10.3797/scipharm.2007.75.179

AMA Style

Tachakittirungrod S, Ikegami F, Okonogi S. Antioxidant Active Principles Isolated from Psidium guajava Grown in Thailand. Scientia Pharmaceutica. 2007; 75(4):179-193. https://doi.org/10.3797/scipharm.2007.75.179

Chicago/Turabian Style

Tachakittirungrod, Suganya, Fumio Ikegami, and Siriporn Okonogi. 2007. "Antioxidant Active Principles Isolated from Psidium guajava Grown in Thailand" Scientia Pharmaceutica 75, no. 4: 179-193. https://doi.org/10.3797/scipharm.2007.75.179

APA Style

Tachakittirungrod, S., Ikegami, F., & Okonogi, S. (2007). Antioxidant Active Principles Isolated from Psidium guajava Grown in Thailand. Scientia Pharmaceutica, 75(4), 179-193. https://doi.org/10.3797/scipharm.2007.75.179

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