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Sci. Pharm.Scientia Pharmaceutica
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30 September 2005

Polymeric Proanthocyanidins from Psidium guajava

,
and
1
School of Pharmacy, The University of Petra, P.O.Box: 961343, Amman, Jordan
2
lnstitut für Pharmazeutische Biologie und Phytochemie, Hittorfstrasse 56, 48149 Münster, Germany
*
Author to whom correspondence should be addressed.
Sci. Pharm.2005, 73(3), 113-125;https://doi.org/10.3797/scipharm.aut-05-10
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Abstract

From the aqueous acetone extract of the leaves of Psidium guajava L. the flavanols catechin and gallocatechin, the procyanidins B1, B2, B3 and two prodelphinidins (gallocatechin - (4α→8) - catechin; gallocatechin - (4α→8) - gallo-catechin) were isolated. A more abundant proanthocyanidin polymer was also isolated, purified and its chemical constitution studied by 13C-NMR and phloroglucinol degradation. The mean molecular weight of the polymer was estimated to be about 9 to 10 flavan-3-ol-units with a ratio of procyanidin: prodelphinidin units at 2 : 1 some of which are derivatized by gallic acid.

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