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Monomethylierte 3-Thiacyclopentylsulfaminsäuren und ihre Süßstoffeigenschaften

Institut rur Phannazeutische Chemie der WestHilisehen Wilhelms-Universität Münster, Hittorfstr. 58-62, 0-48149 Münster, Bundesrepublik Deutschland
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Sci. Pharm. 2000, 68(1), 101-108; https://doi.org/10.3797/scipharm.aut-00-09
Received: 27 October 1999 / Revised: 13 December 1999 / Accepted: 13 December 1999 / Published: 3 January 2000
Methyl-3-thiacyclopentanarnines 4a-c were reacted to their sulfamic acid sodiurn salts 5a-c, and their structures determined.Only sodium 4-methyl-3-thiacyclopentylsulfamate (5b) is sweet. The oxa analogues 8a-b however are tasteless.
Keywords: Methyl-3-thiacyclopentanonoximes; reduction to methyl-3-thiacyclopentanamines; sodiurn methyl-3-oxa- and -3-thiacyclopentylsulfamates Methyl-3-thiacyclopentanonoximes; reduction to methyl-3-thiacyclopentanamines; sodiurn methyl-3-oxa- and -3-thiacyclopentylsulfamates
MDPI and ACS Style

Unterhalt, B.; Kerckhoff, L.; Möllers, M. Monomethylierte 3-Thiacyclopentylsulfaminsäuren und ihre Süßstoffeigenschaften. Sci. Pharm. 2000, 68, 101-108.

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