Next Article in Journal
HBV Core Protein Enhances Cytokine Production
Previous Article in Journal
Ginseng Metabolites on Cancer Chemoprevention: An Angiogenesis Link?
Open AccessArticle

Mosaic Pattern of Lung Attenuation on Chest CT in Patients with Pulmonary Hypertension

Pulmonary and Critical Care Medicine, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Maurizio Battino
Diseases 2015, 3(3), 205-212; https://doi.org/10.3390/diseases3030205
Received: 10 July 2015 / Revised: 21 August 2015 / Accepted: 2 September 2015 / Published: 7 September 2015
A mosaic pattern of lung attenuation on chest computed tomography (CT) may be due to various etiologies. There is limited published data on CT results when used to evaluate pulmonary hypertension (PH). We retrospectively studied the frequency of mosaic pattern in patients with PH and the cause of the PH by diagnostic group, as well as the correlation between the mosaic pattern and the following: demographics, severity of the PH, main pulmonary artery (PA) size, PA/aorta (PA/Ao) ratio, pulmonary function tests (PFT), and ventilation perfusion scan results. Overall, 18% of the cohort had CT mosaic pattern (34/189). Mosaic pattern was present in 17/113 (15%) in Group 1 pulmonary arterial hypertension, 5/13 (28%) in Group 2 pulmonary venous hypertension and 8/50 (16%) in Group 3 PH. Conversely, Group 4 chronic thromboembolic PH was more prevalent in 4/8 (50%). Main PA size, PA/Ao ratio, and segmental perfusion defect were positively associated with mosaic pattern. In contrast, factors such as age, gender, body mass index, functional class, hemodynamic data, and PFT values were not associated with mosaic pattern. Mosaic pattern is not specific as an isolated finding for distinguishing the subtype of PH. View Full-Text
Keywords: mosaic pattern; pulmonary hypertension; chest CT scan; pulmonary artery; screening mosaic pattern; pulmonary hypertension; chest CT scan; pulmonary artery; screening
Show Figures

Figure 1

MDPI and ACS Style

Ussavarungsi, K.; Lee, A.S.; Burger, C.D. Mosaic Pattern of Lung Attenuation on Chest CT in Patients with Pulmonary Hypertension. Diseases 2015, 3, 205-212.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Back to TopTop