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Article

Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target

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Budker Institute of Nuclear Physics, 11 Lavrentiev Ave., 630090 Novosibirsk, Russia
2
Faculty of Physics, Novosibirsk State University, 2 Pirogov Str., 630090 Novosibirsk, Russia
*
Author to whom correspondence should be addressed.
Academic Editors: Ignacio Porras, Silva Bortolussi and Yuan-Hao Liu
Biology 2021, 10(5), 350; https://doi.org/10.3390/biology10050350
Received: 1 April 2021 / Revised: 16 April 2021 / Accepted: 16 April 2021 / Published: 21 April 2021
(This article belongs to the Special Issue Boron Neutron Capture Therapy: From Nuclear Physics to Biomedicine)
A compact neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. The source comprises an original design tandem accelerator, solid lithium target, and a neutron beam shaping assembly. The neutron source is capable of producing the high neutron flux in various energy ranges, from thermal to fast, for boron neutron capture therapy, as well as for other applications. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The Boron Neutron Capture Therapy (BNCT) technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China).
A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The proton beam energy can be varied within a range of 0.6–2.3 MeV, keeping a high-energy stability of 0.1%. The beam current can also be varied in a wide range (from 0.3 mA to 10 mA) with high current stability (0.4%). In the device, neutron flux is generated as a result of the 7Li(p,n)7Be threshold reaction. A beam-shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The BNCT technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China). View Full-Text
Keywords: boron neutron capture therapy; neutron source; charge particle accelerator; lithium target; neutron detector boron neutron capture therapy; neutron source; charge particle accelerator; lithium target; neutron detector
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MDPI and ACS Style

Taskaev, S.; Berendeev, E.; Bikchurina, M.; Bykov, T.; Kasatov, D.; Kolesnikov, I.; Koshkarev, A.; Makarov, A.; Ostreinov, G.; Porosev, V.; Savinov, S.; Shchudlo, I.; Sokolova, E.; Sorokin, I.; Sycheva, T.; Verkhovod, G. Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target. Biology 2021, 10, 350. https://doi.org/10.3390/biology10050350

AMA Style

Taskaev S, Berendeev E, Bikchurina M, Bykov T, Kasatov D, Kolesnikov I, Koshkarev A, Makarov A, Ostreinov G, Porosev V, Savinov S, Shchudlo I, Sokolova E, Sorokin I, Sycheva T, Verkhovod G. Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target. Biology. 2021; 10(5):350. https://doi.org/10.3390/biology10050350

Chicago/Turabian Style

Taskaev, Sergey, Evgenii Berendeev, Marina Bikchurina, Timofey Bykov, Dmitrii Kasatov, Iaroslav Kolesnikov, Alexey Koshkarev, Aleksandr Makarov, Georgii Ostreinov, Vyacheslav Porosev, Sergey Savinov, Ivan Shchudlo, Evgeniia Sokolova, Igor Sorokin, Tatiana Sycheva, and Gleb Verkhovod. 2021. "Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target" Biology 10, no. 5: 350. https://doi.org/10.3390/biology10050350

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