Next Article in Journal / Special Issue
Evaluation of a Computerized Decision Support Intervention to Decrease Use of Anti-Pseudomonal Carbapenems in Penicillin Allergic Patients
Previous Article in Journal / Special Issue
A Review of Quality Measures for Assessing the Impact of Antimicrobial Stewardship Programs in Hospitals
Open AccessArticle

Controversies in Antimicrobial Stewardship: Focus on New Rapid Diagnostic Technologies and Antimicrobials

College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA
Department of Pharmacy, Grady Health System, Atlanta, GA 30303, USA
Department of Pharmacy, The Ohio State University, Wexner Medical Center, Columbus, OH 43210, USA
Department of Pharmacy, University of Florida Health Jacksonville, Jacksonville, FL 32209, USA
Author to whom correspondence should be addressed.
Academic Editors: Christopher C. Butler and Angela Huang
Antibiotics 2016, 5(1), 6;
Received: 29 September 2015 / Revised: 20 December 2015 / Accepted: 6 January 2016 / Published: 14 January 2016
(This article belongs to the Special Issue Antimicrobial Stewardship)
Antimicrobial stewardship programs (ASPs) are challenged with ensuring appropriate antimicrobial use while minimizing expenditures. ASPs have consistently demonstrated improved patient outcomes and significant cost reductions but are continually required to justify the costs of their existence and interventions due to the silo mentality often adopted by hospital administrators. As new technologies and antimicrobials emerge, ASPs are in a constant tug-of-war between providing optimal clinical outcomes and ensuring cost containment. Additionally, robust data on cost-effectiveness of new rapid diagnostic technologies and antimicrobials with subsequent ASP interventions to provide justification are lacking. As the implementation of an ASP will soon be mandatory for acute care hospitals in the United States, ASPs must find ways to justify novel interventions to align themselves with healthcare administrators. This review provides a framework for the justification of implementing a rapid diagnostic test or adding a new antimicrobial to formulary with ASP intervention, reviews approaches to demonstrating cost-effectiveness, and proposes methods for which ASPs may reduce healthcare expenditures via alternative tactics. View Full-Text
Keywords: stewardship; antimicrobial; rapid diagnostic technology; outcomes stewardship; antimicrobial; rapid diagnostic technology; outcomes
MDPI and ACS Style

Wenzler, E.; Wong, J.R.; Goff, D.A.; Jankowski, C.A.; Bauer, K.A. Controversies in Antimicrobial Stewardship: Focus on New Rapid Diagnostic Technologies and Antimicrobials. Antibiotics 2016, 5, 6.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop