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Nanomaterials 2018, 8(9), 681;

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Faculty of Engineering in Foreign Languages, University Politehnica of Bucharest, 313 Splaiul Independenței, Bucharest 060042, Romania
Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gheorghe Polizu Street, Bucharest 011061, Romania
Lasers Department, National Institute for Lasers, Plasma and Radiation Physics, 409 Atomiștilor Street, Magurele 077125, Romania
Research Center for Microscopic Morphology and Immunology, University of Medicine and Pharmacy of Craiova, 2 Petru Rareș Street, Craiova 200349, Romania
Author to whom correspondence should be addressed.
Received: 1 August 2018 / Revised: 24 August 2018 / Accepted: 28 August 2018 / Published: 31 August 2018
PDF [1113 KB, uploaded 3 September 2018]


During the past few years, silver nanoparticles (AgNPs) became one of the most investigated and explored nanotechnology-derived nanostructures, given the fact that nanosilver-based materials proved to have interesting, challenging, and promising characteristics suitable for various biomedical applications. Among modern biomedical potential of AgNPs, tremendous interest is oriented toward the therapeutically enhanced personalized healthcare practice. AgNPs proved to have genuine features and impressive potential for the development of novel antimicrobial agents, drug-delivery formulations, detection and diagnosis platforms, biomaterial and medical device coatings, tissue restoration and regeneration materials, complex healthcare condition strategies, and performance-enhanced therapeutic alternatives. Given the impressive biomedical-related potential applications of AgNPs, impressive efforts were undertaken on understanding the intricate mechanisms of their biological interactions and possible toxic effects. Within this review, we focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based nanostructures. View Full-Text
Keywords: silver nanoparticles; biomedical applications; biological interactions; biofunctional performances; intrinsic anti-inflammatory activity; antimicrobial efficiency silver nanoparticles; biomedical applications; biological interactions; biofunctional performances; intrinsic anti-inflammatory activity; antimicrobial efficiency

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Burdușel, A.-C.; Gherasim, O.; Grumezescu, A.M.; Mogoantă, L.; Ficai, A.; Andronescu, E. Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview. Nanomaterials 2018, 8, 681.

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