Minor Neurological Dysfunctions (MNDs) in Autistic Children without Intellectual Disability
AbstractBackground: Children with autism spectrum disorder (ASD) require neurological evaluation to detect sensory-motor impairment. This will improve understanding of brain function in children with ASD, in terms of minor neurological dysfunctions (MNDs). Methods: We compared 32 ASD children without intellectual disability (IQ ≥ 70) with 32 healthy controls. A standardized and age-specific neurological examination according to Touwen was used to detect the presence of MNDs. Particular attention was paid to severity and type of MNDs. Results: Children with ASD had significantly higher rates of MNDs compared to controls (96.9% versus 15.6%): 81.3% had simple MNDs (p < 0.0001) and 15.6% had complex MNDs (p = 0.053). The prevalence of MNDs in the ASD group was significantly higher (p < 0.0001) than controls. With respect to specific types of MNDs, children with ASD showed a wide range of fine manipulative disability, sensory deficits and choreiform dyskinesia. We also found an excess of associated movements and anomalies in coordination and balance. Conclusions: Results replicate previous findings which found delays in sensory-motor behavior in ASD pointing towards a role for prenatal, natal and neonatal risk factors in the neurodevelopmental theory of autism. View Full-Text
Share & Cite This Article
Tripi, G.; Roux, S.; Carotenuto, M.; Bonnet-Brilhault, F.; Roccella, M. Minor Neurological Dysfunctions (MNDs) in Autistic Children without Intellectual Disability. J. Clin. Med. 2018, 7, 79.
Tripi G, Roux S, Carotenuto M, Bonnet-Brilhault F, Roccella M. Minor Neurological Dysfunctions (MNDs) in Autistic Children without Intellectual Disability. Journal of Clinical Medicine. 2018; 7(4):79.Chicago/Turabian Style
Tripi, Gabriele; Roux, Sylvie; Carotenuto, Marco; Bonnet-Brilhault, Frédérique; Roccella, Michele. 2018. "Minor Neurological Dysfunctions (MNDs) in Autistic Children without Intellectual Disability." J. Clin. Med. 7, no. 4: 79.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.