Can Photoplethysmography Replace Arterial Blood Pressure in the Assessment of Blood Pressure?
School of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Center for Research and Advanced Studies (Cinvestav), Monterrey’s Unit, Apodaca N. L. 66600, México
Nuffield Department of Surgical Sciences, University of Oxford, Oxford 450456, UK
School of Electrical and Electronic Engineering, The University of Adelaide, Adelaide, SA 5005, Australia
Centre for Biomedical Engineering, The University of Adelaide, Adelaide, SA 5005, Australia
Faculty of Medicine, University of British Columbia, Vancouver, BC V1Y 1T3, Canada
BC Children’s & Women’s Hospital, Vancouver, BC V6H 3N1, Canada
Author to whom correspondence should be addressed.
Received: 28 August 2018 / Revised: 19 September 2018 / Accepted: 28 September 2018 / Published: 30 September 2018
Arterial Blood Pressure (ABP) and photoplethysmography (PPG) are both useful techniques to monitor cardiovascular status. Though ABP monitoring is more widely employed, this procedure of signal acquisition whether done invasively or non-invasively may cause inconvenience and discomfort to the patients. PPG, however, is simple, noninvasive, and can be used for continuous measurement. This paper focuses on analyzing the similarities in time and frequency domains between ABP and PPG signals for normotensive, prehypertensive and hypertensive subjects and the feasibility of the classification of subjects considering the results of the analysis performed. From a database with 120 records of ABP and PPG, each 120 s in length, the records where separated into epochs taking into account 10 heartbeats, and the following statistical measures were performed: Correlation (r
), Coherence (COH), Partial Coherence (pCOH), Partial Directed Coherence (PDC), Directed Transfer Function (DTF), Full Frequency Directed Transfer Function (ffDTF) and Direct Directed Transfer Function (dDTF). The correlation coefficient was
on average for all groups, indicating a strong morphology similarity. For COH and pCOH, coherence (linear correlation in frequency domain) was found with significance (p
< 0.01) in differentiating between normotensive and hypertensive subjects using PPG signals. For the dataset at hand, only two synchrony measures are able to convincingly distinguish hypertensive subjects from normotensive control subjects, i.e., ffDTF and dDTF. From PDC, DTF, ffDTF, and dDTF, a consistent, a strong significant causality from ABP→PPG was found. When all synchrony measures were combined, an
accuracy was achieved to detect hypertension using a Neural Network classifier, suggesting that PPG holds most informative features that exist in ABP.
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Martínez, G.; Howard, N.; Abbott, D.; Lim, K.; Ward, R.; Elgendi, M. Can Photoplethysmography Replace Arterial Blood Pressure in the Assessment of Blood Pressure? J. Clin. Med. 2018, 7, 316.
Martínez G, Howard N, Abbott D, Lim K, Ward R, Elgendi M. Can Photoplethysmography Replace Arterial Blood Pressure in the Assessment of Blood Pressure? Journal of Clinical Medicine. 2018; 7(10):316.
Martínez, Gloria; Howard, Newton; Abbott, Derek; Lim, Kenneth; Ward, Rabab; Elgendi, Mohamed. 2018. "Can Photoplethysmography Replace Arterial Blood Pressure in the Assessment of Blood Pressure?" J. Clin. Med. 7, no. 10: 316.
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