Placental Cortisol Dysregulation in Mothers with Experiences of Childhood Adversity: Potential Mechanisms and Clinical Implications
Abstract
:1. Introduction: The Maternal–Placental–Fetal Hypothalamic–Pituitary–Adrenal (HPA) Axis Regulating Fetal Stress
2. The Role of Adverse Childhood Experiences on Placental–Fetal Stress Hormone Cortisol Regulation
3. Connecting the Dots between ACEs and Placental Cortisol Regulation via 11-Beta Hydroxysteroid Dehydrogenase (11β-HSD2)
4. Clinical Implications
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Conflicts of Interest
References
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George, J.; Muzik, M.; Townsel, C. Placental Cortisol Dysregulation in Mothers with Experiences of Childhood Adversity: Potential Mechanisms and Clinical Implications. J. Clin. Med. 2024, 13, 2020. https://doi.org/10.3390/jcm13072020
George J, Muzik M, Townsel C. Placental Cortisol Dysregulation in Mothers with Experiences of Childhood Adversity: Potential Mechanisms and Clinical Implications. Journal of Clinical Medicine. 2024; 13(7):2020. https://doi.org/10.3390/jcm13072020
Chicago/Turabian StyleGeorge, Joshua, Maria Muzik, and Courtney Townsel. 2024. "Placental Cortisol Dysregulation in Mothers with Experiences of Childhood Adversity: Potential Mechanisms and Clinical Implications" Journal of Clinical Medicine 13, no. 7: 2020. https://doi.org/10.3390/jcm13072020
APA StyleGeorge, J., Muzik, M., & Townsel, C. (2024). Placental Cortisol Dysregulation in Mothers with Experiences of Childhood Adversity: Potential Mechanisms and Clinical Implications. Journal of Clinical Medicine, 13(7), 2020. https://doi.org/10.3390/jcm13072020