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Volume 13
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10.3390/jcm13030786
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Background:
Systematic Review

Lack of Consensus on the Definition of Aseptic Loosening in Total Ankle Replacement: A Narrative Systematic Review

by
Peter Kvarda
1,*,
Andreea Mills
2,
David Shepherd
1 and
Tim Schneider
1
1
Melbourne Orthopaedic Group, 33 The Avenue, Windsor, Melbourne, VIC 3181, Australia
2
Royal Australasian College of Surgeons, Victoria State Office, 250-290 Spring Street, Melbourne, VIC 3002, Australia
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2024, 13(3), 786; https://doi.org/10.3390/jcm13030786
Submission received: 23 December 2023 / Revised: 23 January 2024 / Accepted: 27 January 2024 / Published: 30 January 2024
(This article belongs to the Section Orthopedics)
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Abstract

Background: Aseptic loosening is one of the most common modes of failure of total ankle replacement (TAR). However, a precise definition of aseptic loosening is still lacking. This systematic review aimed to identify the variations of applied definitions and offer insights into the lack of consensus. Methods: Human studies reporting aseptic loosening of TAR published in peer-reviewed journals within the last decade were considered. The search strategy involved specific terms in Embase, MEDLINE ALL, and the Cochrane Library. Variations in aseptic loosening definitions were analysed. Results: Of 767 studies, 88 were included in this study. Only nine studies precisely defined aseptic loosening with significant variations. Twenty-two studies referenced the term and fifty-seven reported it as a complication but neither defined nor referenced it. Conclusions: Significant uncertainty exists regarding the universal definition of aseptic loosening of TAR, and many variations occur in terms of the assessment approach and criteria.
Keywords: aseptic loosening; total ankle replacement; failure; definition; consensus aseptic loosening; total ankle replacement; failure; definition; consensus

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MDPI and ACS Style

Kvarda, P.; Mills, A.; Shepherd, D.; Schneider, T. Lack of Consensus on the Definition of Aseptic Loosening in Total Ankle Replacement: A Narrative Systematic Review. J. Clin. Med. 2024, 13, 786. https://doi.org/10.3390/jcm13030786

AMA Style

Kvarda P, Mills A, Shepherd D, Schneider T. Lack of Consensus on the Definition of Aseptic Loosening in Total Ankle Replacement: A Narrative Systematic Review. Journal of Clinical Medicine. 2024; 13(3):786. https://doi.org/10.3390/jcm13030786

Chicago/Turabian Style

Kvarda, Peter, Andreea Mills, David Shepherd, and Tim Schneider. 2024. "Lack of Consensus on the Definition of Aseptic Loosening in Total Ankle Replacement: A Narrative Systematic Review" Journal of Clinical Medicine 13, no. 3: 786. https://doi.org/10.3390/jcm13030786

APA Style

Kvarda, P., Mills, A., Shepherd, D., & Schneider, T. (2024). Lack of Consensus on the Definition of Aseptic Loosening in Total Ankle Replacement: A Narrative Systematic Review. Journal of Clinical Medicine, 13(3), 786. https://doi.org/10.3390/jcm13030786

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