Potential Relationships between the Median Nerve Cross-Sectional Area and Physical Characteristics in Unilateral Symptomatic Carpal Tunnel Syndrome Patients
Abstract
1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- de Krom, M.C.; Knipschild, P.G.; Kester, A.D.; Thijs, C.T.; Boekkooi, P.F.; Spaans, F. Carpal tunnel syndrome: Prevalence in the general population. J. Clin. Epidemiol. 1992, 45, 373–376. [Google Scholar] [CrossRef] [PubMed]
- Atroshi, I.; Gummesson, C.; Johnsson, R.; Ornstein, E.; Ranstam, J.; Rosén, I. Prevalence of carpal tunnel syndrome in a general population. JAMA 1999, 282, 153–158. [Google Scholar] [CrossRef]
- Bland, J.D.P.; Rudolfer, S.M. Clinical surveillance of carpal tunnel syndrome in two areas of the United Kingdom, 1991–2001. J. Neurol. Neurosurg. Psychiatry 2003, 74, 1674. [Google Scholar] [CrossRef] [PubMed]
- Ibrahim, I.; Khan, W.S.; Goddard, N.; Smitham, P. Carpal tunnel syndrome: A review of the recent literature. Open Orthop. J. 2012, 6, 69–76. [Google Scholar] [CrossRef] [PubMed]
- MacDermid, J.C.; Wessel, J. Clinical diagnosis of carpal tunnel syndrome: A systematic review. J. Hand Ther. 2004, 17, 309–319. [Google Scholar] [CrossRef]
- Graham, B. The value added by electrodiagnostic testing in the diagnosis of carpal tunnel syndrome. J. Bone Jt. Surg. Am. 2008, 90, 2587–2593. [Google Scholar] [CrossRef]
- Fowler, J.R.; Cipolli, W.; Hanson, T. A Comparison of Three Diagnostic Tests for Carpal Tunnel Syndrome Using Latent Class Analysis. J. Bone Jt. Surg. Am. 2015, 97, 1958–1961. [Google Scholar] [CrossRef]
- Lee, D.; van Holsbeeck, M.T.; Janevski, P.K.; Ganos, D.L.; Ditmars, D.M.; Darian, V.B. Diagnosis of carpal tunnel syndrome. Ultrasound versus electromyography. Radiol. Clin. N. Am. 1999, 37, 859–872. [Google Scholar] [CrossRef]
- Wong, S.M.; Griffith, J.F.; Hui, A.C.; Lo, S.K.; Fu, M.; Wong, K.S. Carpal tunnel syndrome: Diagnostic usefulness of sonography. Radiology 2004, 232, 93–99. [Google Scholar] [CrossRef]
- Pulikkottil, B.J.; Schub, M.; Kadow, T.R.; Wang, W.; Fowler, J.R. Correlating Median Nerve Cross-sectional Area With Nerve Conduction Studies. J. Hand Surg. Am. 2016, 41, 958–962. [Google Scholar] [CrossRef]
- Wessel, L.E.; Marshall, D.C.; Stepan, J.G.; Sacks, H.A.; Nwawka, O.K.; Miller, T.T.; Fufa, D.T. Sonographic Findings Associated With Carpal Tunnel Syndrome. J. Hand Surg. Am. 2019, 44, 374–381. [Google Scholar] [CrossRef]
- Yoshii, Y.; Zhao, C.; Amadio, P.C. Recent advances in ultrasound diagnosis of carpal tunnel syndrome. Diagnostics 2020, 10, 596. [Google Scholar] [CrossRef] [PubMed]
- Sugimoto, H.; Miyaji, N.; Ohsawa, T. Carpal tunnel syndrome: Evaluation of median nerve circulation with dynamic contrast-enhanced MR imaging. Radiology 1994, 190, 459–466. [Google Scholar] [CrossRef] [PubMed]
- Stevens, J.C. AAEM minimonograph #26: The electrodiagnosis of carpal tunnel syndrome. American Association of Electrodiagnostic Medicine. Muscle Nerve 1997, 20, 1477–1486. [Google Scholar] [PubMed]
- Shiri, R. Hypothyroidism and carpal tunnel syndrome: A meta-analysis. Muscle Nerve 2014, 50, 879–883. [Google Scholar] [CrossRef] [PubMed]
- Padua, L.; Di Pasquale, A.; Pazzaglia, C.; Liotta, G.A.; Librante, A.; Mondelli, M. Systematic review of pregnancy-related carpal tunnel syndrome. Muscle Nerve 2010, 42, 697–702. [Google Scholar] [CrossRef] [PubMed]
- Pourmemari, M.H.; Shiri, R. Diabetes as a risk factor for carpal tunnel syndrome: A systematic review and meta-analysis. Diabet. Med. 2016, 33, 10–16. [Google Scholar] [CrossRef]
- Shiri, R.; Pourmemari, M.H.; Falah-Hassani, K.; Viikari-Juntura, E. The effect of excess body mass on the risk of carpal tunnel syndrome: A meta-analysis of 58 studies. Obes. Rev. 2015, 16, 1094–1104. [Google Scholar] [CrossRef]
- Bland, J.D. Treatment of carpal tunnel syndrome. Muscle Nerve 2007, 36, 167–171. [Google Scholar] [CrossRef]
- Nancollas, M.P.; Peimer, C.A.; Wheeler, D.R.; Sherwin, F.S. Long-term results of carpal tunnel release. J. Hand Surg. Br. 1995, 20, 470–474. [Google Scholar] [CrossRef]
- Festen-Schrier, V.; Amadio, P.C. The biomechanics of subsynovial connective tissue in health and its role in carpal tunnel syndrome. J. Electromyogr. Kinesiol. 2018, 38, 232–239. [Google Scholar] [CrossRef]
- Vilensky, J.A.; Gilman, S.; Casey, K. Sir Victor Horsley, Mr John Marshall, the nervi nervorum, and pain: More than a century ahead of their time. Arch. Neurol. 2005, 62, 499–501. [Google Scholar] [CrossRef] [PubMed]
- Sunderland, S. The nerve lesion in the carpal tunnel syndrome. J. Neurol. Neurosurg. Psychiatry 1976, 39, 615–626. [Google Scholar] [CrossRef] [PubMed]
- Jinrok, O.; Zhao, C.; Amadio, P.C.; An, K.N.; Zobitz, M.E.; Wold, L.E. Vascular pathologic changes in the flexor tenosynovium (subsynovial connective tissue) in idiopathic carpal tunnel syndrome. J. Orthop. Res. 2004, 22, 1310–1315. [Google Scholar] [CrossRef]
- Stecco, C.; Giordani, F.; Fan, C.; Biz, C.; Pirri, C.; Frigo, A.C.; Fede, C.; Macchi, V.; Masiero, S.; De Caro, R. Role of fasciae around the median nerve in pathogenesis of carpal tunnel syndrome: Microscopic and ultrasound study. J. Anat. 2020, 236, 660–667. [Google Scholar] [CrossRef]
- Kudo, T.; Yoshii, Y.; Hara, Y.; Ogawa, T.; Ishii, T. Clinical Relevance of Ultrasonographic and Electrophysiological Findings of the Median Nerve in Unilateral Carpal Tunnel Syndrome Patients. Diagnostics 2022, 12, 2799. [Google Scholar] [CrossRef]
- Yoshii, Y.; Tanaka, T.; Ishii, T. Correlations of Median Nerve Area, Strain, and Nerve Conduction in Carpal Tunnel Syndrome Patients. Hand 2016, 11, 161–167. [Google Scholar] [CrossRef]
- Cohen, J. Statistical Power Analysis for the Behavioral Sciences, 2nd ed.; Routledge: Abingdon, UK, 1988. [Google Scholar]
- Ng, A.J.T.; Chandrasekaran, R.; Prakash, A.; Mogali, S.R. A systematic review: Normative reference values of the median nerve cross-sectional area using ultrasonography in healthy individuals. Sci. Rep. 2022, 12, 9217. [Google Scholar] [CrossRef]
- Nakamichi, K.; Tachibana, S. Ultrasonographic measurement of median nerve cross-sectional area in idiopathic carpal tunnel syndrome: Diagnostic accuracy. Muscle Nerve 2002, 26, 798–803. [Google Scholar] [CrossRef]
- Hobson-Webb, L.D.; Massey, J.M.; Juel, V.C.; Sanders, D.B. The ultrasonographic wrist-to-forearm median nerve area ratio in carpal tunnel syndrome. Clin. Neurophysiol. 2008, 119, 1353–1357. [Google Scholar] [CrossRef] [PubMed]
- Yesildag, A.; Kutluhan, S.; Sengul, N.; Koyuncuoglu, H.R.; Oyar, O.; Guler, K.; Gulsoy, U.K. The role of ultrasonographic measurements of the median nerve in the diagnosis of carpal tunnel syndrome. Clin. Radiol. 2004, 59, 910–915. [Google Scholar] [CrossRef]
- Sernik, R.A.; Abicalaf, C.A.; Pimentel, B.F.; Braga-Baiak, A.; Braga, L.; Cerri, G.G. Ultrasound features of carpal tunnel syndrome: A prospective case-control study. Skelet. Radiol. 2008, 37, 49–53. [Google Scholar] [CrossRef] [PubMed]
- Seror, P. Sonography and electrodiagnosis in carpal tunnel syndrome diagnosis, an analysis of the literature. Eur. J. Radiol. 2008, 67, 146–152. [Google Scholar] [CrossRef] [PubMed]
- Fowler, J.R.; Gaughan, J.P.; Ilyas, A.M. The sensitivity and specificity of ultrasound for the diagnosis of carpal tunnel syndrome: A meta-analysis. Clin. Orthop. Relat. Res. 2011, 469, 1089–1094. [Google Scholar] [CrossRef]
- Torres-Costoso, A.; Martínez-Vizcaíno, V.; Álvarez-Bueno, C.; Ferri-Morales, A.; Cavero-Redondo, I. Accuracy of Ultrasonography for the Diagnosis of Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis. Arch. Phys. Med. Rehabil. 2018, 99, 758–765.e710. [Google Scholar] [CrossRef]
- Kang, K.-H.; Lee, G.-H.; Choi, G.-E.; Hyun, K.-Y. Mean Value of Median Nerve Cross-sectional Area in Healthy 20s and 30s in Busan Area. Biomed. Sci. Lett. 2020, 26, 186–191. [Google Scholar] [CrossRef]
- Cartwright, M.S.; Mayans, D.R.; Gillson, N.A.; Griffin, L.P.; Walker, F.O. Nerve cross-sectional area in extremes of age. Muscle Nerve 2013, 47, 890–893. [Google Scholar] [CrossRef] [PubMed]
- Tahmaz, M.; Yoon, M.S.; Schellinger, P.D.; Philipps, J. Cross-sectional area in median and ulnar nerve ultrasound correlates with hand volume. Muscle Nerve 2020, 62, 83–88. [Google Scholar] [CrossRef]
- Kotb, M.A.; Bedewi, M.A.; Aldossary, N.M.; Mahmoud, G.; Naguib, M.F. Sonographic assessment of carpal tunnel syndrome in diabetic patients with and without polyneuropathy. Medicine 2018, 97, e11104. [Google Scholar] [CrossRef]
- Demino, C.; Fowler, J.R. Comparison of Borderline Ultrasound and Nerve Conduction Studies for Carpal Tunnel Syndrome. Hand 2020, 17, 860–864. [Google Scholar] [CrossRef]
- Bowers, E.M.R.; Como, C.J.; Dooley, S.W.; Morales-Restrepo, A.; Fowler, J.R. Magnetic Resonance Imaging-Measured Cross-Sectional Area of the Median Nerve. J. Hand Surg. Glob. Online 2022, 4, 93–96. [Google Scholar] [CrossRef] [PubMed]
- Kuliasha, C.A.; Spearman, B.S.; Atkinson, E.W.; Furniturewalla, A.; Rustogi, P.; Mobini, S.; Nunamaker, E.B.; Brennan, A.B.; Otto, K.J.; Schmidt, C.E.; et al. Robust and Scalable Tissue-Engineerined Electronic Nerve Interfaces (Teeni). Solid-State Sens. Actuators Microsyst. Work. 2018, 46–49. [Google Scholar]
- Reina, M.A.; López, A.; De Andrés, J.A. Adipose tissue within peripheral nerves. Study of the human sciatic nerve. Rev. Esp. Anestesiol. Reanim. 2002, 49, 397–402. [Google Scholar]
- Agarwal, S.; Haase, S.C. Lipofibromatous hamartoma of the median nerve. J. Hand Surg. Am. 2013, 38, 392–397; quiz 397. [Google Scholar] [CrossRef] [PubMed]
- Lam, N.; Thurston, A. Association of obesity, gender, age and occupation with carpal tunnel syndrome. Aust. N. Z. J. Surg. 1998, 68, 190–193. [Google Scholar] [CrossRef]
- Ferry, S.; Hannaford, P.; Warskyj, M.; Lewis, M.; Croft, P. Carpal tunnel syndrome: A nested case-control study of risk factors in women. Am. J. Epidemiol. 2000, 151, 566–574. [Google Scholar] [CrossRef]
- Bland, J.D. The relationship of obesity, age, and carpal tunnel syndrome: More complex than was thought? Muscle Nerve 2005, 32, 527–532. [Google Scholar] [CrossRef]
Age (Years Old) | Height (cm) * | Weight (kg) * | BMI | |
---|---|---|---|---|
Males | 67.5 ± 9.4 | 165.9 ± 5.3 | 66.9 ± 12.9 | 24.2 ± 3.8 |
Females | 64.0 ± 12.1 | 153.2 ± 6.5 | 58.4 ± 10.3 | 24.9 ± 3.9 |
Total | 65.3 ± 11.3 | 157.6 ± 8.6 | 61.3 ± 11.9 | 24.6 ± 3.8 |
Category | Symptomatic Side | Asymptomatic Side | |
---|---|---|---|
Distal latency * | 1 | 3 | 25 |
2 | 26 | 42 | |
3 | 22 | 4 | |
4 | 7 | 0 | |
5 | 3 | 0 | |
6 | 15 | 0 | |
Sensory nerve conduction velocity * | 1 | 18 | 51 |
2 | 21 | 11 | |
3 | 1 | 0 | |
4 | 27 | 1 |
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Ikumi, A.; Yoshii, Y.; Kudo, T.; Kohyama, S.; Ogawa, T.; Hara, Y.; Ishii, T. Potential Relationships between the Median Nerve Cross-Sectional Area and Physical Characteristics in Unilateral Symptomatic Carpal Tunnel Syndrome Patients. J. Clin. Med. 2023, 12, 2515. https://doi.org/10.3390/jcm12072515
Ikumi A, Yoshii Y, Kudo T, Kohyama S, Ogawa T, Hara Y, Ishii T. Potential Relationships between the Median Nerve Cross-Sectional Area and Physical Characteristics in Unilateral Symptomatic Carpal Tunnel Syndrome Patients. Journal of Clinical Medicine. 2023; 12(7):2515. https://doi.org/10.3390/jcm12072515
Chicago/Turabian StyleIkumi, Akira, Yuichi Yoshii, Takamasa Kudo, Sho Kohyama, Takeshi Ogawa, Yuki Hara, and Tomoo Ishii. 2023. "Potential Relationships between the Median Nerve Cross-Sectional Area and Physical Characteristics in Unilateral Symptomatic Carpal Tunnel Syndrome Patients" Journal of Clinical Medicine 12, no. 7: 2515. https://doi.org/10.3390/jcm12072515
APA StyleIkumi, A., Yoshii, Y., Kudo, T., Kohyama, S., Ogawa, T., Hara, Y., & Ishii, T. (2023). Potential Relationships between the Median Nerve Cross-Sectional Area and Physical Characteristics in Unilateral Symptomatic Carpal Tunnel Syndrome Patients. Journal of Clinical Medicine, 12(7), 2515. https://doi.org/10.3390/jcm12072515